1 hasil untuk "Burhan Ceylan"

Fluorescence HPLC Analysis of Teriflunomide in Human Plasma Following Derivatization with 4-Chloro-7-Nitrobenzofurazan: Method Development and Application to a Prototype Pharmacokinetic Evaluation

Meltem Cayci; Burhan Ceylan; Cem Onal

Pharmaceuticals, Vol. 19 No. 7 · 2026 · Inggris · DOAJ Scopus

Background/Objectives: Teriflunomide is an active metabolite of leflunomide and acts as a selective and reversible inhibitor of dihydroorotate dehydrogenase, a key enzyme in de novo pyrimidine biosynthesis. It exhibits immunomodulatory activity by reducing the proliferation of activated T and B…