49 hasil untuk "XU Li-jun"
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Artikel Jurnal Teks lengkap
New role for ceramide in hypoxia and insulin resistance
Ceramides are significant metabolic products of sphingolipids in lipid metabolism and are associated with insulin resistance and hepatic steatosis. In chronic inflammatory pathological conditions, hypoxia occurs, the metabolism of ceramide changes, and insulin resistance arises. Hypoxia-inducible…
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Base-iodine-promoted metal-catalyst-free reactions of [60]fullerene with β-keto esters for the selective formation of [60]fullerene derivatives
In this study, methanofullerenes and 2′,3′-dihydrofuran C(60) derivatives were selectively synthesized in high yields via the reactions of C(60) with β-keto esters under mild conditions by controlling the addition sequence and molar ratio of iodine and base. The structures of the products were…
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Research on screening and evaluation of suitable oat varieties in the Liangshan region
The experiment aimed to screen for oat varieties suitable for both grain and forage use in the Liangshan region. The trial selected five new oat varieties and measured agronomic traits, yield, nutritional components, etc. The results showed that Baiyan No.10 had the highest plant height, effective…
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Comprehensive evaluation of production performance of 15 oat varieties in south bank of Yellow River in western Inner Mongolia
The experiment was to comprehensively evaluate the production performance of 15 oat varieties in south bank of Yellow River in western Inner Mongolia. A total of 15 oat varieties were planted in Dalat banner, Ordos City, Inner Mongolia in 2021. The membership function of 15 oat varieties was…
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Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition
Major progress has been made clinically in inhibiting the programmed death receptor 1 (PD-1)/PD-L1 interaction to enhance T cell-mediated immune function, yet the effectiveness of anti-PD-L1/PD-1 agents in enhancing natural killer (NK) cell’s function remains largely unknown. Susceptibilities of…
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Tetramethylpyrazine Ameliorates Lipopolysaccharide-Induced Sepsis in Rats via Protecting Blood–Brain Barrier, Impairing Inflammation and Nitrous Oxide Systems
The aim of this study was to assess the underlying impact of Tetramethylpyrazine (TMP), which is the main activity compound of Ligusticum chuanxiong Hort, on the blood–brain barrier, inflammatory and nitrous oxide systems in a rat model of lipopolysaccharide (LPS)-induced sepsis. The SD rats were…
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Effects of a Comprehensive Intervention Program of Static-Dynamic Balance Training Combined with Reminiscence Therapy on the Level of Healthy Aging Among Older Adults in a Rural Community: A Randomized Controlled Trial
PURPOSE: Healthy aging levels are generally low among rural older adults, yet the effects of combined static-dynamic balance training and reminiscence therapy on this population remain underexplored. This study evaluated the efficacy of a combined static-dynamic balance training and reminiscence…
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Comprehensive evaluation of production performance of 10 oat varieties in Panxi region
The experiment was to screen the varieties of oat suitable for autumn sowing and feeding in idle winter fields in Panxi region. In the experiment, 10 oat varieties were planted in Xichang in November 2021, the yield performance and nutritional quality of oat were measured, and the comprehensive…
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Effect of different row spacing on yield and silage quality of oat 'Fuyan 70'
The study was to explore the optimal row space configuration for high-quality and efficient production of 'Fuyan 70' in Hulun Buir area. A single factor randomized block design was used to study the effect of row spacing of 15, 20, 25, 30 and 35 cm on yield and silage quality. The grey relational…
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Radiation alters PD-L1/NKG2D ligand levels in lung cancer cells and leads to immune escape from NK cell cytotoxicity via IL-6-MEK/Erk signaling pathway
We investigated whether radiation influences the susceptibility of non-small cell lung cancer (NSCLC) cells to NK cell mediated cytotoxicity. We found radiation treatment increased expression of programmed cell death ligand 1 (PD-L1), but decreased NK group 2, member D (NKG2D) ligand expressions in…
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Emergence of Invasive Serotype Ib Sequence Type 10 Group B Streptococcus Disease in Chinese Infants Is Driven by a Tetracycline-Sensitive Clone
BACKGROUND: Group B streptococcus (GBS) is a leading cause of serious infections in infants. The extensive use of tetracycline has led to the selection of specific resistant and infectious GBS clones. The sequence type (ST) 10 GBS strain, causing invasive infections in infants, is becoming…
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miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo
MicroRNAs (miRNA) are short (~22 nt) single stranded RNAs that downregulate gene expression. Although recent studies indicate extensive miRNA changes in response to ischemic brain injury, there is currently little information on the roles of specific miRNAs in this setting. Heat shock proteins…
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Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats
AIM: To investigate the molecular mechanisms of berberine inhibition of hepatic gluconeogenesis in a diabetic rat model. METHODS: The 40 rats were randomly divided into five groups. One group was selected as the normal group. In the remaining groups (n = 8 each), the rats were fed on a high-fat…
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Isolation and passage of muscle-derived stem cells from the rat penile corpora cavernosa and induction of differentiation into smooth muscle cells
This study treated the isolation and passage of muscle-derived stem cells (MDSCs) from rat penile corpora cavernosa, detection of stem cell marker expression, observation of their self-renewal and continuous proliferation, and demonstration of their potential to differentiate into smooth muscle…
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The therapeutic value of SC66 in human renal cell carcinoma cells
The PI3K-AKT-mTOR cascade is required for renal cell carcinoma (RCC) progression. SC66 is novel AKT inhibitor. We found that SC66 inhibited viability, proliferation, migration and invasion of RCC cell lines (786-O and A498) and patient-derived primary RCC cells. Although SC66blocked AKT-mTORC1/2…
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Screening of functional genes affecting the quality of translucent eggshell membranes based on RNA-seq analysis and DIA proteomics
The quality of eggshells holds substantial economic significance and serves as a critical selection criterion in poultry breeding. Eggshell translucency significantly impairs their aesthetic quality, which is structurally attributed to the thinning of the eggshell membrane or reduced tensile…
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Effect of natural garlic essential oil on immune indexes of chickens infected with Coccidia
The study was to study the effect of natural garlic essential oil added to drinking water on immune indexes of chicks infected with Eimeria tenella. Four hundred Nongda No. 3 grain egg chicks were randomly divided into five groups, with four replicates in each group and 20 chicks in each replicate…
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Sequencing and analysis of John Cunningham polyomavirus DNA from acquired immunodeficiency syndrome patients with progressive multifocal leukoencephalopathy
Supplemental Digital Content is available in the text
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Further screening of SNP loci of eggshell translucency related genes and evaluation of genetic effects
Eggshell translucency is a widespread issue in the field of egg quality. Previous research has established that the heritability of eggshell translucency is relatively low or moderate. Scientists have also successfully identified SNP loci related to eggshell translucency on different chromosomes by…
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Effects of beak-treatment styles on beak morphology and production performance of layer chicks aged 0–8 weeks
INTRODUCTION: Double-infrared (IR-D) and laser energy sources (LAS) are two types of newly beak treatment equipment. Although the IR-D and LAS techniques have been developed by changing the number and type of energy sources, their effects on layer chicks are yet to be systematically studied…