131 hasil untuk "Bress, Adam"
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Artikel Jurnal Teks lengkap
“Approaching drug choices and challenges for the management of hypertension”
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Artikel Jurnal Teks lengkap
Role of cytochrome P450 genotype in the steps toward personalized drug therapy
Genetic polymorphism for cytochrome 450 (P450) enzymes leads to interindividual variability in the plasma concentrations of many drugs. In some cases, P450 genotype results in decreased enzyme activity and an increased risk for adverse drug effects. For example, individuals with the CYP2D6…
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Artikel Jurnal Teks lengkap
Revisiting Warfarin Dosing Using Machine Learning Techniques
Determining the appropriate dosage of warfarin is an important yet challenging task. Several prediction models have been proposed to estimate a therapeutic dose for patients. The models are either clinical models which contain clinical and demographic variables or pharmacogenetic models which…
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Artikel Jurnal Teks lengkap
Response to Letter Regarding Article, “Cost-Effectiveness of Intensive Versus Standard Blood Pressure Control”
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Artikel Jurnal Teks lengkap
Use of Telehealth and Antihypertensive Medications Among US Adults with Hypertension
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Artikel Jurnal Teks lengkap
Association of New Use of Antihypertensives That Stimulate vs Inhibit Type 2 and 4 Angiotensin II Receptors With Dementia Among Medicare Beneficiaries
IMPORTANCE: Prevalent use of antihypertensive medications that stimulate type 2 and 4 angiotensin II receptors, compared with those that do not stimulate these receptors, has been associated with a lower risk of dementia. However, previous studies were limited by inclusion of individuals with…
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Artikel Jurnal Teks lengkap
β-Amyloid Positron Emission Tomography Use Across Medicare Administrative Contractor Regions
This cross-sectional study assesses variation in β-amyloid positron emission tomography (PET) use among Medicare beneficiaries with mild cognitive impairment or dementia by Medicare Administrative Contractor region.
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Artikel Jurnal Teks lengkap
Self-perceived bodyweight status among adults who are overweight or have obesity, with and without high cardiovascular risk
BACKGROUND: Accurate self-perception of body weight status is important for patient engagement and effective management of overweight and obesity. We estimated the prevalence of misperceived weight status and lack of clinician counseling among US adults who meet criteria for being overweight or…
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Artikel Jurnal Teks lengkap
Genetic ancestry as an effect modifier of naltrexone in smoking cessation among African Americans: an analysis of a randomized controlled trial
OBJECTIVES: To determine if there were differential quit rates between AA and European Americans (EA) with the experimental treatment naltrexone, and examine the role of genetic ancestry on these outcomes among AAs. METHODS: Data from a previous randomized trial of 315 smokers to naltrexone vs…
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Artikel Jurnal Teks lengkap
Relationship Between ACE2 and Other Components of the Renin-Angiotensin System
PURPOSE OF THE REVIEW: Angiotensin-converting enzyme 2 (ACE2) is a key counter-regulatory component of the renin-angiotensin system. Here, we briefly review the mechanistic and target organ effects related to ACE2 activity, and the importance of ACE2 in SARS-CoV-2 infection. RECENT FINDINGS: ACE2…
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Artikel Jurnal Teks lengkap
Generalizability of SPRINT Results to the U.S. Adult Population
BACKGROUND: In SPRINT (Systolic Blood Pressure Intervention Trial), a systolic blood pressure (SBP) goal of
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Artikel Jurnal Teks lengkap
Association of Ambient Temperature and Blood Pressure in the Jackson Heart Study
Extreme temperature events related to climate change may impact blood pressure (BP). African American populations are disproportionately affected by temperature extremes due to structural inequities. We examined the association between ambient outdoor temperature and BP among participants in JHS, a…