73 hasil untuk "Bugert, Peter"
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Artikel Jurnal Teks lengkap
The Gears Keep Turning: Current Progress in Platelet Function Testing
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Artikel Jurnal Teks lengkap
Clinical and Laboratory Diagnosis of Inherited Platelet Function Disorders
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Artikel Jurnal Teks lengkap
100 Years after von Dungern & Hirschfeld: Kinship Investigation from Blood Groups to SNPs
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Artikel Jurnal Teks lengkap
Pathogen Reduction in Blood Products: What's Behind These Techniques?
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Artikel Jurnal Teks lengkap
Innate Immune System for Diagnostics and Therapy: Progress in Fundamental Knowledge and Clinical Application
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Artikel Jurnal Teks lengkap
Spotlight on HLA: Current Aspects in Transfusion and Transplantation Medicine
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Artikel Jurnal Teks lengkap
Evaluation of Single Nucleotide Variants in Intron 1 of the ABO Gene as Diagnostic Markers for the A(1) Blood Group
INTRODUCTION: The molecular diagnosis of the A(1) blood group is based on the exclusion of ABO gene variants causing blood groups A(2), B, or O. A specific genetic marker for the A(1) blood group is still missing. Recently, long-read ABO sequencing revealed four sequence variations in intron 1 as…
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Artikel Jurnal Teks lengkap
Optimized PCR with sequence specific primers (PCR-SSP) for fast and efficient determination of Interleukin-6 Promoter -597/-572/-174Haplotypes
Abstract Background Interleukin-6 (IL-6) promoter polymorphisms at positions -597(G→A), -572(G→C) and -174(G→C) were shown to have a clinical impact on different major diseases. At present PCR-SSP protocols for IL-6 -597/-572/-174haplotyping are elaborate and require large amounts of genomic DNA…
Juga tersedia di: PubMed Central
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Artikel Jurnal Teks lengkap
Blood Group ABO Genotyping in Paternity Testing
BACKGROUND: The ABO blood groups result from DNA sequence variations, predominantly single nucleotide and insertion/deletion polymorphisms (SNPs and indels), in the ABO gene encoding a glycosyltransferase. The ABO blood groups A(1), A(2), B and O predominantly result from the wild type allele A1…
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Artikel Jurnal Teks lengkap
The Effect of Psychoactive Drugs on in vitro Platelet Function
BACKGROUND: Neuro-hormonal and hemostatic mechanisms are important in a wide range of psychological and cardiovascular diseases. The use of psychoactive drugs in mental illnesses is often involved with hematologic side effects including impaired platelet function. Subsequently, the risk for the…
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Artikel Jurnal Teks lengkap
Introduction of an Optimized Protocol for Long-Read Nanopore Sequencing of Blood Group Genes in Immunohematology Case Studies
INTRODUCTION: In immunohematology case studies the knowledge about variants of the blood group gene of interest can facilitate antibody diagnosis. Known gene variants can be rapidly genotyped by specific methods, but the identification of unknown variants requires sequencing of the gene. High…
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Artikel Jurnal Teks lengkap
Introduction of Noninvasive Prenatal Testing for Blood Group and Platelet Antigens from Cell-Free Plasma DNA Using Digital PCR
BACKGROUND: Noninvasive prenatal testing (NIPT) for fetal antigens is a common standard for targeted immune prophylaxis in RhD-mediated hemolytic disease of the fetus and newborn, and is most frequently done by quantitative PCR (qPCR). A similar approach is considered for other blood group and…
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Artikel Jurnal Teks lengkap
Development of Anti-G, Anti-C and Anti-Jk(b) in a 22-Year-Old Mother during Her Fourth Pregnancy
BACKGROUND: Anti-G antibodies are rarely found since anti-D, in combination with anti-C, are difficult to discriminate from anti-G antibodies in routine testing. CASE REPORT: A 22-year-old, gravida-3, para-1, woman with blood group A Rh D neg ccddee and known antibody anti-Jk(b), gave birth to her…
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Artikel Jurnal Teks lengkap
A Single-Tube Real-Time PCR Assay for Mycoplasma Detection as a Routine Quality Control of Cell Therapeutics
BACKGROUND: Contamination of cell culture and biological material by mollicute species is an important safety issue and requires testing. We have developed a singletube real-time polymerase chain reaction (PCR) assay for rapid detection of Mollicutes species stipulated by the European Pharmacopeia…
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Artikel Jurnal Teks lengkap
Towards a Regional Registry of Extended Typed Blood Donors: Molecular Typing for Blood Group, Platelet and Granulocyte Antigens
BACKGROUND: The provision of compatible blood products to patients is the most essential task of transfusion medicine. Besides ABO and Rh, a number of additional blood group antigens often have to be considered for the blood supply of immunized or chronically transfused patients. It also applies…