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Preferred Supramolecular Organization and Dimer Interfaces of Opioid Receptors from Simulated Self-Association

Davide Provasi; Mustafa Burak Boz; Jennifer M. Johnston dkk.

PLOS Computational Biology, Vol. 11 No. 3 · 2015 · Inggris · PLOS Scopus

Substantial evidence in support of the formation of opioid receptor (OR) di-/oligomers suggests previously unknown mechanisms used by these proteins to exert their biological functions. In an attempt to guide experimental assessment of the identity of the minimal signaling unit for ORs, we…