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Rivaroxaban improves vascular response in LPS-induced acute inflammation in experimental models

Armond Daci; Lorenzo Da Dalt; Rame Alaj dkk.

PLOS ONE, Vol. 15 No. 12 · 2020 · Inggris · PLOS Scopus

Rivaroxaban (RVX) was suggested to possess anti-inflammatory and vascular tone modulatory effects. The goal of this study was to investigate whether RVX impacts lipopolysaccharide (LPS)-induced acute vascular inflammatory response. Male rats were treated with 5 mg/kg RVX (oral gavage) followed by…