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2 hasil untuk "Burkhard Madea"

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  1. Artikel Jurnal Teks lengkap

    Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

    Manja Wachsmuth; Alexander Hübner; Mingkun Li dkk.

    PLOS Genetics, Vol. 12 No. 3 · 2016 · Inggris · PLOS Scopus

    The mitochondrial (mt) genome is present in many copies in human cells, and intra-individual variation in mtDNA sequences is known as heteroplasmy. Recent studies found that heteroplasmies are highly tissue-specific, site-specific, and allele-specific, however the functional implications have not…

  2. Artikel Jurnal Teks lengkap

    Staurosporine and Extracellular Matrix Proteins Mediate the Conversion of Small Cell Lung Carcinoma Cells into a Neuron-Like Phenotype

    Tamara Murmann; Carmen Carrillo-García; Nadine Veit dkk.

    PLoS ONE, Vol. 9 No. 2 · 2014 · Inggris · PLOS Scopus

    Small cell lung carcinomas (SCLCs) represent highly aggressive tumors with an overall five-year survival rate in the range of 5 to 10%. Here, we show that four out of five SCLC cell lines reversibly develop a neuron-like phenotype on extracellular matrix constituents such as fibronectin, laminin or…