1 hasil untuk "C. Fuchs"

Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation

Jamie Bates; Archana Vijayakumar; Sarani Ghoshal dkk.

Journal of Hepatology · 2020 · Inggris · OpenAlex Scopus

BACKGROUND & AIMS: Non-alcoholic steatohepatitis (NASH) is a chronic liver disease characterized by hepatic lipid accumulation, inflammation, and progressive fibrosis. Acetyl-CoA carboxylase (ACC) catalyzes the rate-limiting step of de novo lipogenesis and regulates fatty acid β-oxidation in…