12 hasil untuk "C. Fuchs"

Selective Reduction of AMPA Currents onto Hippocampal Interneurons Impairs Network Oscillatory Activity

Antonio Caputi; Elke C. Fuchs; Kevin Allen dkk.

PLoS ONE, Vol. 7 No. 6 · 2012 · Inggris · PLOS Scopus

Reduction of excitatory currents onto GABAergic interneurons in the forebrain results in impaired spatial working memory and altered oscillatory network patterns in the hippocampus. Whether this phenotype is caused by an alteration in hippocampal interneurons is not known because most studies…

Trends in Prevalence of Hypertension in Brazil: A Systematic Review with Meta-Analysis

Rafael V. Picon; Flávio D. Fuchs; Leila B. Moreira dkk.

PLoS ONE, Vol. 7 No. 10 · 2012 · Inggris · PLOS Scopus

Background: The prevalence of hypertension in emerging nations was scarcely described to date. In Brazil, many population-based surveys evaluated the prevalence in cities throughout the country. However, there is no population-based nationwide study of prevalence of hypertension. In this study, we…

Effect of diacerein on renal function and inflammatory cytokines in participants with type 2 diabetes mellitus and chronic kidney disease: A randomized controlled trial

Fabiana Piovesan; Glaucia S. Tres; Leila B. Moreira dkk.

PLOS ONE, Vol. 12 No. 10 · 2017 · Inggris · PLOS Scopus

Diacerein seems to improve metabolic control and reduce inflammatory marker levels in individuals with type 2 diabetes mellitus (Type 2 DM), but for participants with chronic kidney disease (CKD) its effect is unknown. This study aimed to evaluate the effect of diacerein vs. placebo on urinary…

Non-Thermal Dielectric Barrier Discharge (DBD) Effects on Proliferation and Differentiation of Human Fibroblasts Are Primary Mediated by Hydrogen Peroxide

Julian Balzer; Kiara Heuer; Erhan Demir dkk.

PLOS ONE, Vol. 10 No. 12 · 2015 · Inggris · PLOS Scopus

The proliferation of fibroblasts and myofibroblast differentiation are crucial in wound healing and wound closure. Impaired wound healing is often correlated with chronic bacterial contamination of the wound area. A new promising approach to overcome wound contamination, particularly infection with…

Hearing Loss in a Mouse Model of 22q11.2 Deletion Syndrome

Jennifer C. Fuchs; Fhatarah A. Zinnamon; Ruth R. Taylor dkk.

PLoS ONE, Vol. 8 No. 11 · 2013 · Inggris · PLOS Scopus

22q11.2 Deletion Syndrome (22q11DS) arises from an interstitial chromosomal microdeletion encompassing at least 30 genes. This disorder is one of the most significant known cytogenetic risk factors for schizophrenia, and can also cause heart abnormalities, cognitive deficits, hearing difficulties…

Correction: Hearing Loss in a Mouse Model of 22q11.2 Deletion Syndrome

Jennifer C. Fuchs; Fhatarah A. Zinnamon; Ruth R. Taylor dkk.

PLoS ONE, Vol. 9 No. 1 · 2014 · Inggris · PLOS Scopus

Are Retinal Vessels Calibers Influenced by Blood Pressure Measured at the Time of Retinography Acquisition?

Sandra C. Fuchs; Helena M. Pakter; Marcelo K. Maestri dkk.

PLOS ONE, Vol. 10 No. 9 · 2015 · Inggris · PLOS Scopus

Background: Retinal arterial narrowing is associated with higher office blood pressure (BP) and ambulatory blood pressure monitoring, and increased incidence of cardiovascular disease, but it is still unknown if the vessel caliber is associated with BP measured at the time of retinography…

Immune Suppressive Effect of Cinnamaldehyde Due to Inhibition of Proliferation and Induction of Apoptosis in Immune Cells: Implications in Cancer

Franziska Roth-Walter; Anna Moskovskich; Cristina Gomez-Casado dkk.

PLoS ONE, Vol. 9 No. 10 · 2014 · Inggris · PLOS Scopus

Background: Besides its anti-inflammatory effects, cinnamaldehyde has been reported to have anti-carcinogenic activity. Here, we investigated its impact on immune cells. Methods: Activation of nuclear factor-κB by cinnamaldehyde (0–10 µg/ml) alone or in combination with lipopolysaccharide was…

Effects of combined training performed two or four times per week on 24-h blood pressure, glycosylated hemoglobin and other health-related outcomes in aging individuals with hypertension: Rationale and study protocol of a randomized clinical trial

Rodrigo Ferrari; Lucas Betti Domingues; Leandro de Oliveira Carpes dkk.

PLOS ONE, Vol. 16 No. 5 · 2021 · Inggris · PLOS Scopus

Background: Acute blood pressure lowering after exercise seems to predict the extent of blood pressure reduction after chronic exercise training interventions. Based on that, the same weekly amount of exercise performed more frequently could be more beneficial for controlling blood pressure…

Co-Infection by Hepatitis C Virus in HIV-Infected Patients in Southern Brazil: Genotype Distribution and Clinical Correlates

Fernando H. Wolff; Sandra C. Fuchs; Nêmora N. T. Barcellos dkk.

PLoS ONE, Vol. 5 No. 5 · 2010 · Inggris · PLOS Scopus

Background: Prevalence rates of Hepatitis C Virus (HCV) co-infection, the distribution of HCV genotypes, and the frequency of spontaneous resolution of hepatitis C in patients infected with the Human Immunodeficiency Virus (HIV) have a worldwide disparity. The purpose of this study is to…

Alcohol Drinking Pattern: A Comparison between HIV-Infected Patients and Individuals from the General Population

Maria Leticia R. Ikeda; Nemora T. Barcellos; Paulo R. Alencastro dkk.

PLOS ONE, Vol. 11 No. 6 · 2016 · Inggris · PLOS Scopus

Background: Alcohol consumption is highly prevalent in the general population and among HIV-infected population. This study aimed to compare the pattern of alcohol consumption and to describe characteristics associated with heavy alcohol consumption in individuals from the general population with…

Host Genetics Predict Clinical Deterioration in HCV-Related Cirrhosis

Lindsay Y. King; Kara B. Johnson; Hui Zheng dkk.

PLoS ONE, Vol. 9 No. 12 · 2014 · Inggris · PLOS Scopus

Single nucleotide polymorphisms (SNPs) in the epidermal growth factor (EGF, rs4444903), patatin-like phospholipase domain-containing protein 3 (PNPLA3, rs738409) genes, and near the interleukin-28B (IL28B, rs12979860) gene are linked to treatment response, fibrosis, and hepatocellular carcinoma…