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3 results for "Casson, Adam"

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  1. Journal Article Full text

    Independent real‐world application of a clinical‐grade automated prostate cancer detection system

    da Silva, Leonard M; Pereira, Emilio M; Salles, Paulo GO et al.

    J Pathol · 2021 · English · PubMed Central

    Artificial intelligence (AI)‐based systems applied to histopathology whole‐slide images have the potential to improve patient care through mitigation of challenges posed by diagnostic variability, histopathology caseload, and shortage of pathologists. We sought to define the performance of an…

  2. Journal Article Full text

    A foundation model for clinical-grade computational pathology and rare cancers detection

    Vorontsov, Eugene; Bozkurt, Alican; Casson, Adam et al.

    Nat Med · 2024 · English · PubMed Central

    The analysis of histopathology images with artificial intelligence aims to enable clinical decision support systems and precision medicine. The success of such applications depends on the ability to model the diverse patterns observed in pathology images. To this end, we present Virchow, the…

  3. Journal Article Full text

    A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms

    Pareja, Fresia; Dopeso, Higinio; Wang, Yi Kan et al.

    Cancer Res · 2024 · English · PubMed Central

    Artificial intelligence (AI)-systems can improve cancer diagnosis, yet their development often relies on subjective histological features as ground truth for training. Here, we developed an AI-model applied to histological whole-slide images (WSIs) using CDH1 bi-allelic mutations, pathognomonic for…