14 hasil untuk "Chang, Jiaming"
Menampilkan 1–14 · 0,30 detik · RSS
-
Preprint Teks lengkap
PhyUnfold-Net: Advancing Remote Sensing Change Detection with Physics-Guided Deep Unfolding
Bi-temporal change detection is highly sensitive to acquisition discrepancies, including illumination, season, and atmosphere, which often cause false alarms. We observe that genuine changes exhibit higher patch-wise singular-value entropy (SVE) than pseudo changes in the feature-difference space…
-
Artikel Jurnal Teks lengkap
Comparative Clinical Study Between Modified Ureteral Orthotopic Reimplantation and Cohen Method Under Pneumovesicum in Pediatric Patients With Hydroureteronephrosis
Purpose: To report our initial experience with a modified ureteral orthotopic reimplantation technique under pneumovesicum and compare the outcomes vs. those obtained with the Cohen technique under pneumovesicum for the correction of primary obstructive megaureter (POM) or vesicoureteral…
-
Artikel Jurnal Teks lengkap
Graphdiyne and Nitrogen-Doped Graphdiyne Nanotubes as Highly Efficient Electrocatalysts for Oxygen Reduction Reaction
Electrocatalysts with high efficiency and low cost are always urgently needed for oxygen reduction reaction (ORR). As a new carbon allotrope, graphdiyne (GDY) has received much attention due to its unique chemical structure containing sp- and sp(2)-hybridized carbons, and intrinsic electrochemical…
-
Artikel Jurnal Teks lengkap
miR‐100 rs1834306 a > G polymorphism decreases neuroblastoma risk in Chinese children
BACKGROUND: Neuroblastoma is a common malignant tumor stemming from the sympathetic nervous system in children, which is often life‐threatening. The genetics of neuroblastoma remains unclear. Studies have shown that miRNAs participate in the regulation of a broad spectrum of biological pathways…
-
Artikel Jurnal Teks lengkap
Functional polymorphisms of the TET1 gene increase the risk of neuroblastoma in Chinese children
Common genetic mutations are absent in neuroblastoma, one of the most common childhood tumours. As a demethylase of 5‐methylcytosine (m5C) modification, TET1 plays an important role in tumourigenesis and differentiation. However, the association between TET1 gene polymorphisms and susceptibility to…
-
Artikel Jurnal Teks lengkap
Association between MYCN gene polymorphisms and neuroblastoma susceptibility: a case-control study in Chinese children from Jiangsu Province
BACKGROUND: Neuroblastoma, developed from the sympathetic nervous system, is a deadly childhood malignancy. There is an urgent need to elucidate its intricated etiology. MYCN amplification leads to aggressive neuroblastoma and represents a powerful marker of poor prognosis. However, the correlation…
-
Artikel Jurnal Teks lengkap
Associations of CCAT2 gene polymorphisms with neuroblastoma susceptibility in children from Jiangsu province
BACKGROUND: The CCAT2 gene is associated with carcinogenesis, but its effect on neuroblastoma, the most common extracranial tumor in children, remains unclear. METHODS: We conducted a case–control study involving 402 children with neuroblastoma and 473 children without neuroblastoma. TaqMan…
-
Artikel Jurnal Teks lengkap
MiR-100 rs1834306 A>G Increases Biliary Atresia Risk in Southern Han Chinese Children
BACKGROUND: Biliary atresia (BA) is a type of severe cholestatic childhood disease that may have a genetic component. miR-100 plays a key role in regulating cell apoptosis, proliferation, and inflammatory reactions. A single-nucleotide polymorphism in miR-100 has been proven to modulate…
-
Artikel Jurnal Teks lengkap
Polymorphisms in the NSUN1 gene and neuroblastoma risk in Chinese children from Jiangsu province
Neuroblastoma is the most prevalent extracranial solid tumor among children and exhibits remarkable heterogeneity. The methylation of cytosine to form 5-methylcytosine (m5C) is the primary type of modification found in DNA and RNA. The NOL1/NOP2/sun (NSUN) family, specifically NSUN1, is responsible…
-
Artikel Jurnal Teks lengkap
Associations of NEFL gene polymorphisms with neuroblastoma risk in Chinese children from Jiangsu Province
BACKGROUND: Neuroblastoma is the predominant extracranial solid tumor occurring in children, and genetic factors like genetic polymorphism play a crucial role in its etiology. In this study, we investigated the associations between three NEFL polymorphisms (rs11994014 G>A, rs2979704 T>C, and…
-
Artikel Jurnal Teks lengkap
Genetic variants of m(1)A modification genes and the risk of neuroblastoma: novel insights from a Chinese case-control study
BACKGROUND: The N(1)-adenosine methylation (m(1)A) modification plays a significant role in various cancers. However, the functions of m(1)A modification genes and their variants in neuroblastoma remain to be elucidated. METHODS: We conducted a case-control study involving 402 neuroblastoma…
-
Artikel Jurnal Teks lengkap
Improving neuroblastoma risk prediction through a polygenic risk score derived from genome-wide association study-identified loci
OBJECTIVE: Neuroblastoma is the most common extracranial solid tumor in children and has complex genetic underpinnings. Previous genome-wide association studies (GWASs) have identified many loci associated with neuroblastoma susceptibility; however, their application in risk prediction for Chinese…
-
Artikel Jurnal Teks lengkap
Association of TRDMT1 Gene Polymorphisms With Neuroblastoma Susceptibility: Insights From a Case–Control Study
Neuroblastoma is the most common extracranial solid tumour in children, and genetic susceptibility plays a crucial role in its development. The impact of tRNA Dimethyltransferase 1 (TRDMT1), a primary methyltransferase catalysing 5‐methylcytosine (m5C) RNA modification, on neuroblastoma…
-
Artikel Jurnal Teks lengkap
CD14(+)CD16(−) monocytes exhibit NF-κB hyperactivation in biliary atresia: Clinical association and murine therapeutic validation
BACKGROUND: Classical CD14(+)CD16(−) monocytes are elevated in biliary atresia (BA); however, their specific role in bile duct injury and the underlying regulatory mechanisms remain unclear. This study aimed to define their contribution to BA pathogenesis, focusing on the NF-κB signaling pathway…