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2 hasil untuk "Cihan Di"

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  1. Artikel Jurnal

    Insulin resistance (TyG index) and body mass index as metabolic biomarker combined with ApoE genotype to diagnose Alzheimer’s disease

    Renyu Chen; Shiyu Fan; Cihan Di dkk.

    Frontiers in Aging Neuroscience, Vol. 18 · 2026 · Inggris · DOAJ Scopus

    BackgroundGrowing evidence suggests that both ApoE genotype and metabolic disturbances including insulin resistance (IR) and obesity constitute risk factors for Alzheimer’s disease (AD). However, large-scale studies investigating whether ApoE genotype interacts with metabolic abnormalities to…

  2. Artikel Jurnal

    Association of ε4 with cerebrospinal fluid protein and amyloid-β levels in Alzheimer's disease

    Renyu Chen; Fang Yuan; Shuai Liu dkk.

    Journal of Alzheimer's Disease Reports, Vol. 9 · 2025 · Inggris · DOAJ Scopus

    Background Alzheimer's disease (AD) is a neurodegenerative disease, with APOE ε4 as the most common genetic risk factor. This protein has been implicated in amyloid-β peptide (Aβ)-mediated pathological processes in patients with AD. However, the mechanism by which APOE ε4 regulates cerebrospinal…