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162 hasil untuk "Deepa"

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  1. Artikel Jurnal Teks lengkap

    The road not taken: Could stress-specific mutations lead to different evolutionary paths?

    Deepa Agashe

    PLOS Biology, Vol. 15 No. 6 · 2017 · Inggris · PLOS Scopus

    Organisms often encounter stressful conditions, some of which damage their DNA. In response, some organisms show a high expression of error-prone DNA repair machinery, causing a temporary increase in the genome-wide mutation rate. Although we now have a detailed map of the molecular mechanisms…

  2. Artikel Jurnal Teks lengkap

    The red flour beetle Tribolium castaneum : A model for host-microbiome interactions

    Aparna Agarwal; Deepa Agashe

    PLOS ONE, Vol. 15 No. 10 · 2020 · Inggris · PLOS Scopus

    A large body of ongoing research focuses on understanding the mechanisms and processes underlying host-microbiome interactions, and predicting their ecological and evolutionary outcomes. To draw general conclusions about such interactions and understand how they are established, we must synthesize…

  3. Artikel Jurnal Teks lengkap

    Mutation bias alters the distribution of fitness effects of mutations

    Mrudula Sane; Shazia Parveen; Deepa Agashe

    PLOS Biology, Vol. 23 No. 7 · 2025 · Inggris · PLOS Scopus

    Mutation bias is an important factor determining the diversity of genetic variants available for selection. As adaptation proceeds and some beneficial mutations are fixed, new beneficial mutations become rare, limiting further adaptation. The depletion of beneficial mutations is especially stark…

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  1. Artikel Jurnal Teks lengkap

    Protective Effect of Curcumin on Pulmonary and Cardiovascular Effects Induced by Repeated Exposure to Diesel Exhaust Particles in Mice

    Abderrahim Nemmar; Deepa Subramaniyan; Badreldin H. Ali

    PLoS ONE, Vol. 7 No. 6 · 2012 · Inggris · PLOS Scopus

    Particulate air pollution has been associated with increased risk of cardiopulmonary diseases. However, the underlying mechanisms are not fully understood. We have previously demonstrated that single dose exposure to diesel exhaust particle (DEP) causes lung inflammation and peripheral thrombotic…

  2. Artikel Jurnal Teks lengkap

    Global mistranslation increases cell survival under stress in Escherichia coli

    Laasya Samhita; Parth K. Raval; Deepa Agashe

    PLOS Genetics, Vol. 16 No. 3 · 2020 · Inggris · PLOS Scopus

    Mistranslation is typically deleterious for cells, although specific mistranslated proteins can confer a short-term benefit in a particular environment. However, given its large overall cost, the prevalence of high global mistranslation rates remains puzzling. Altering basal mistranslation levels…

  3. Artikel Jurnal Teks lengkap

    Self-compassion as a protective factor against adverse consequences of social media use: A scoping review

    Deepa Manjanatha; Nicole Pippard; Cinnamon S. Bloss

    PLOS One, Vol. 20 No. 5 · 2025 · Inggris · PLOS Scopus

    Self-compassion has been shown to foster wellbeing and act as a protective factor against the development of psychopathology. Its protective capacity against adverse consequences of social media use, however, is not well understood. Given the increasing use of social media in our daily lives…

  4. Artikel Jurnal Teks lengkap

    Spatial Probability Dynamically Modulates Visual Target Detection in Chickens

    Devarajan Sridharan; Deepa L. Ramamurthy; Eric I. Knudsen

    PLoS ONE, Vol. 8 No. 5 · 2013 · Inggris · PLOS Scopus

    The natural world contains a rich and ever-changing landscape of sensory information. To survive, an organism must be able to flexibly and rapidly locate the most relevant sources of information at any time. Humans and non-human primates exploit regularities in the spatial distribution of relevant…

  5. Artikel Jurnal Teks lengkap

    Subcutaneous hydration and medications infusions (effectiveness, safety, acceptability): A systematic review of systematic reviews

    Daphne Broadhurst; Marie Cooke; Deepa Sriram dkk.

    PLOS ONE, Vol. 15 No. 8 · 2020 · Inggris · PLOS Scopus

    Objective: To synthesize the current evidence for subcutaneous hydration and medication infusions from systematic reviews and to assess their methodological quality. Introduction: Peripheral intravascular cannula/catheter insertion is a common invasive procedure for administering fluids and…

  6. Artikel Jurnal Teks lengkap

    A Sensitive High-Throughput Assay for Evaluating Host-Pathogen Interactions in Cryptococcus neoformans Infection

    Deepa Srikanta; Meng Yang; Matthew Williams dkk.

    PLoS ONE, Vol. 6 No. 7 · 2011 · Inggris · PLOS Scopus

    Background: Cryptococcus neoformans causes serious disease in immunocompromised individuals, leading to over 600,000 deaths per year worldwide. Part of this impact is due to the organism's ability to thwart what should be the mammalian hosts' first line of defense against cryptococcal infection…

  7. Artikel Jurnal Teks lengkap

    Japanese Encephalitis Virus Disrupts Cell-Cell Junctions and Affects the Epithelial Permeability Barrier Functions

    Tanvi Agrawal; Vats Sharvani; Deepa Nair dkk.

    PLoS ONE, Vol. 8 No. 7 · 2013 · Inggris · PLOS Scopus

    Japanese encephalitis virus (JEV) is a neurotropic flavivirus, which causes viral encephalitis leading to death in about 20–30% of severely-infected people. Although JEV is known to be a neurotropic virus its replication in non-neuronal cells in peripheral tissues is likely to play a key role in…

  8. Artikel Jurnal Teks lengkap

    Activation of p38/JNK Pathway Is Responsible for Embelin Induced Apoptosis in Lung Cancer Cells: Transitional Role of Reactive Oxygen Species

    Deepa R. Avisetti; K. Suresh Babu; Shasi V. Kalivendi

    PLoS ONE, Vol. 9 No. 1 · 2014 · Inggris · PLOS Scopus

    The natural product embelin has been demonstrated to possess a wide range of therapeutic properties, however, the mechanisms by which it exerts anticancer effects are not yet clear. By monitoring the molecular changes associated during early apoptotic phase, we have identified the crucial role of…

  9. Artikel Jurnal Teks lengkap

    The effects of exercise on neuromuscular function in people with chronic neck pain: A systematic review and meta-analysis

    Angelo Marco Dirito; Deepa Abichandani; Ferozkhan Jadhakhan dkk.

    PLOS ONE, Vol. 19 No. 12 · 2024 · Inggris · PLOS Scopus

    Background: Differences in cervical neuromuscular function are commonly observed between people with and without chronic neck pain. Exercise may improve cervical neuromuscular function of people with neck pain although the evidence for this has not been systematically reviewed. Objective: To…

  10. Artikel Jurnal Teks lengkap

    A meta-analysis and systematic review of changes in joint position sense and static standing balance in patients with whiplash-associated disorder

    Masood Mazaheri; Deepa Abichandani; Idsart Kingma dkk.

    PLOS ONE, Vol. 16 No. 4 · 2021 · Inggris · PLOS Scopus

    Objective: To synthesise and analyse the current evidence regarding changes in joint position sense (JPS) and standing balance in people with whiplash-associated disorder (WAD) taking the presence or absence of dizziness into account. Data sources: PubMed, CINAHL Plus, Web of Science, Embase…

  11. Artikel Jurnal Teks lengkap

    Unintended exposure to e-liquids and subsequent health outcomes among US youth and adults

    Juhan Lee; Grace Kong; Suchitra Krishnan-Sarin dkk.

    PLOS ONE, Vol. 19 No. 7 · 2024 · Inggris · PLOS Scopus

    This study aimed to determine the prevalence and predictors of oral, ocular, or dermal e-liquid exposure and subsequent outcomes (becoming sick, going to the hospital) in the US. We examined survey data from the Population Assessment of Tobacco and Health Study Wave 5 (2018–2019). The analytic…

  12. Artikel Jurnal Teks lengkap

    Hydrodynamic Radii of Intrinsically Disordered Proteins Determined from Experimental Polyproline II Propensities

    Maria E. Tomasso; Micheal J. Tarver; Deepa Devarajan dkk.

    PLOS Computational Biology, Vol. 12 No. 1 · 2016 · Inggris · PLOS Scopus

    The properties of disordered proteins are thought to depend on intrinsic conformational propensities for polyproline II (PPII) structure. While intrinsic PPII propensities have been measured for the common biological amino acids in short peptides, the ability of these experimentally determined…

  13. Artikel Jurnal Teks lengkap

    Insights from deconvolution of cell subtype proportions enhance the interpretation of functional genomic data

    Yu Kong; Deepa Rastogi; Cathal Seoighe dkk.

    PLOS ONE, Vol. 14 No. 4 · 2019 · Inggris · PLOS Scopus

    Cell subtype proportion variability between samples contributes significantly to the variation of functional genomic properties such as gene expression or DNA methylation. Although the impact of the variation of cell subtype composition on measured genomic quantities is recognized, and some…

  14. Artikel Jurnal Teks lengkap

    Phenotypic diversity of Methylobacterium associated with rice landraces in North-East India

    Pratibha Sanjenbam; Radhika Buddidathi; Radhika Venkatesan dkk.

    PLOS ONE, Vol. 15 No. 2 · 2020 · Inggris · PLOS Scopus

    The ecology and distribution of many bacteria is strongly associated with specific eukaryotic hosts. However, the impact of such host association on bacterial ecology and evolution is not well understood. Bacteria from the genus Methylobacterium consume plant-derived methanol, and are some of the…

  15. Artikel Jurnal Teks lengkap

    Antioxidant, antibacterial, in vitro, and in silico α-glucosidase inhibition activities and chemical profiling of Usnea cornuta Korb

    Deepa Karki; Anuraj Phunyal; Tika Ram Lamichhane dkk.

    PLOS One, Vol. 21 No. 6 · 2026 · Inggris · PLOS Scopus

    The total phenolic content and flavonoid content of the Usnea cornuta extract were evaluated as 210.31 ± 2.87 mg GAE/g and 22.42 ± 0.78 mg QE/g, respectively. The crude extract exhibited strong antioxidant activity (IC50: 32.91 ± 1.27 µg/mL) and notable anti-diabetic effects via α-glucosidase…

  16. Artikel Jurnal Teks lengkap

    High Throughput Transcriptome Profiling of Lithium Stimulated Human Mesenchymal Stem Cells Reveals Priming towards Osteoblastic Lineage

    Neeraj Kumar Satija; Deepa Sharma; Farhat Afrin dkk.

    PLoS ONE, Vol. 8 No. 1 · 2013 · Inggris · PLOS Scopus

    Human mesenchymal stem cells (hMSCs) present in the bone marrow are the precursors of osteoblasts, chondrocytes and adipocytes, and hold tremendous potential for osteoregenerative therapy. However, achieving directed differentiation into osteoblasts has been a major concern. The use of lithium for…

  17. Artikel Jurnal Teks lengkap

    Analysis of Effects of Meteorological Factors on Dengue Incidence in Sri Lanka Using Time Series Data

    Kensuke Goto; Balachandran Kumarendran; Sachith Mettananda dkk.

    PLoS ONE, Vol. 8 No. 5 · 2013 · Inggris · PLOS Scopus

    In tropical and subtropical regions of eastern and South-eastern Asia, dengue fever (DF) and dengue hemorrhagic fever (DHF) outbreaks occur frequently. Previous studies indicate an association between meteorological variables and dengue incidence using time series analyses. The impacts of…