4 hasil untuk "Deepa Sharma"
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Artikel Jurnal Teks lengkap
High Throughput Transcriptome Profiling of Lithium Stimulated Human Mesenchymal Stem Cells Reveals Priming towards Osteoblastic Lineage
Human mesenchymal stem cells (hMSCs) present in the bone marrow are the precursors of osteoblasts, chondrocytes and adipocytes, and hold tremendous potential for osteoregenerative therapy. However, achieving directed differentiation into osteoblasts has been a major concern. The use of lithium for…
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Artikel Jurnal Teks lengkap
Optimization of microbubble enhancement of hyperthermia for cancer therapy in an in vivo breast tumour model
We have demonstrated that exposing human breast tumour xenografts to ultrasound-stimulated microbubbles enhances tumour cell death and vascular disruption resulting from hyperthermia treatment. The aim of this study was to investigate the effect of varying the hyperthermia and ultrasound-stimulated…
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Artikel Jurnal Teks lengkap
Evaluating the effects of radiation and acoustically-stimulated microbubble therapy in an in vivo breast cancer model
Ultrasound-stimulated microbubbles (USMB) cause localized vascular effects and sensitize tumors to radiation therapy (XRT). We investigated acoustic parameter optimization for combining USMB and XRT. We treated breast cancer xenograft tumors with 500 kHz pulsed ultrasound at varying pressures (570…
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Artikel Jurnal Teks lengkap
Ultrasound microbubble potentiated enhancement of hyperthermia-effect in tumours
It is now well established that for tumour growth and survival, tumour vasculature is an important element. Studies have demonstrated that ultrasound-stimulated microbubble (USMB) treatment causes extensive endothelial cell death leading to tumour vascular disruption. The subsequent rapid vascular…