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  1. Artikel Jurnal Teks lengkap

    Systematic evaluation of pigment-based whole-cell lead biosensors: challenges in genetic circuit engineering and critical considerations for background noise control

    Guo, Yan; Deng, Li-dan; Gong, Wen-wu dkk.

    Front Bioeng Biotechnol · 2026 · Inggris · PubMed Central

    INTRODUCTION: Despite advances in whole-cell biosensors for Pb(II) detection, background leakage and limited dynamic range hinder field deployment. This study systematically evaluates four diverse pbr operons and optimizes genetic circuit architectures to develop high-performance pigment-based…