5 hasil untuk "Eric Vittinghoff"

Atypical Femur Fracture Risk versus Fragility Fracture Prevention with Bisphosphonates

Dennis M. Black; Erik J. Geiger; Richard Eastell dkk.

New England Journal of Medicine · 2020 · Inggris · OpenAlex Scopus

BACKGROUND: Bisphosphonates are effective in reducing hip and osteoporotic fractures. However, concerns about atypical femur fractures have contributed to substantially decreased bisphosphonate use, and the incidence of hip fractures may be increasing. Important uncertainties remain regarding the…

Treatment-related changes in bone mineral density as a surrogate biomarker for fracture risk reduction: meta-regression analyses of individual patient data from multiple randomised controlled trials

Dennis M. Black; Douglas C. Bauer; Eric Vittinghoff dkk.

The Lancet Diabetes & Endocrinology · 2020 · Inggris · OpenAlex Scopus

Effects of Time-Restricted Eating on Weight Loss and Other Metabolic Parameters in Women and Men With Overweight and Obesity

Dylan A Lowe; Nancy Wu; Linnea Rohdin-Bibby dkk.

JAMA Internal Medicine · 2020 · Inggris · OpenAlex Scopus

Importance: The efficacy and safety of time-restricted eating have not been explored in large randomized clinical trials. Objective: To determine the effect of 16:8-hour time-restricted eating on weight loss and metabolic risk markers. Interventions: Participants were randomized such that the…

Association Between Cumulative Low-Density Lipoprotein Cholesterol Exposure During Young Adulthood and Middle Age and Risk of Cardiovascular Events

Yiyi Zhang; Mark J. Pletcher; Eric Vittinghoff dkk.

JAMA Cardiology · 2021 · Inggris · OpenAlex Scopus

Importance: Low-density lipoprotein cholesterol (LDL-C) is a major risk factor for cardiovascular disease (CVD). Most observational studies on the association between LDL-C and CVD have focused on LDL-C level at a single time point (usually in middle or older age), and few studies have…

Postexposure Doxycycline to Prevent Bacterial Sexually Transmitted Infections

Anne F. Luetkemeyer; Deborah J Donnell; Julia C. Dombrowski dkk.

New England Journal of Medicine · 2023 · Inggris · OpenAlex Scopus

BACKGROUND: Interventions to reduce sexually transmitted infections (STIs) among men who have sex with men (MSM) are needed. METHODS: (chlamydia), or syphilis in the past year. Participants were randomly assigned in a 2:1 ratio to take 200 mg of doxycycline within 72 hours after condomless sex…