24 results for "Eric Vittinghoff"

Serosorting Is Associated with a Decreased Risk of HIV Seroconversion in the EXPLORE Study Cohort

Susan S. Philip; Xuesong Yu; Deborah Donnell et al.

PLoS ONE, Vol. 5 No. 9 · 2010 · English · PLOS Scopus

Background: Seroadaptation strategies such as serosorting and seropositioning originated within communities of men who have sex with men (MSM), but there are limited data about their effectiveness in preventing HIV transmission when utilized by HIV-negative men. Methodology/Principal Findings: Data…

False Positive Rate of Rapid Oral Fluid HIV Tests Increases as Kits Near Expiration Date

Shelley N. Facente; Teri Dowling; Eric Vittinghoff et al.

PLoS ONE, Vol. 4 No. 12 · 2009 · English · PLOS Scopus

Background: Because a recent cluster of false positive results on the OraQuick ADVANCE® Rapid HIV-1/2 Antibody Test occurred in San Francisco on test kits close to their expiration date, we decided to assess the relationship between time to expiration and rate of false positive results from tests…

Young Adult Exposure to Cardiovascular Risk Factors and Risk of Events Later in Life: The Framingham Offspring Study

Mark J. Pletcher; Eric Vittinghoff; Anusorn Thanataveerat et al.

PLOS ONE, Vol. 11 No. 5 · 2016 · English · PLOS Scopus

Background: It is unclear whether coronary heart disease (CHD) risk factor exposure during early adulthood contributes to CHD risk later in life. Our objective was to analyze whether extent of early adult exposures to systolic and diastolic blood pressure (SBP, DBP) and low-and high-density…

Seroadaptive Practices: Association with HIV Acquisition among HIV-Negative Men Who Have Sex with Men

Snigdha Vallabhaneni; Xin Li; Eric Vittinghoff et al.

Public Library of Science · 2012 · English · PLOS Scopus

Background: Although efficacy is unknown, many men who have sex with men (MSM) attempt to reduce HIV risk by adapting condom use, partner selection, or sexual position to the partner’s HIV serostatus. We assessed the association of seroadaptive practices with HIV acquisition. Methodology/Principal…

Past alcohol consumption and incident atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study

Shalini Dixit; Alvaro Alonso; Eric Vittinghoff et al.

PLOS ONE, Vol. 12 No. 10 · 2017 · English · PLOS Scopus

Background: Although current alcohol consumption is a risk factor for incident atrial fibrillation (AF), the more clinically relevant question may be whether alcohol cessation is associated with a reduced risk. Methods and results: We studied participants enrolled in the Atherosclerosis Risk in…

Correction: Past alcohol consumption and incident atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) Study

Shalini Dixit; Alvaro Alonso; Eric Vittinghoff et al.

PLOS ONE, Vol. 12 No. 12 · 2017 · English · PLOS Scopus

Decreases in Community Viral Load Are Accompanied by Reductions in New HIV Infections in San Francisco

Moupali Das; Priscilla Lee Chu; Glenn-Milo Santos et al.

PLoS ONE, Vol. 5 No. 6 · 2010 · English · PLOS Scopus

Background: At the individual level, higher HIV viral load predicts sexual transmission risk. We evaluated San Francisco's community viral load (CVL) as a population level marker of HIV transmission risk. We hypothesized that the decrease in CVL in San Francisco from 2004–2008, corresponding with…

Behavioral intervention to reduce opioid overdose among high-risk persons with opioid use disorder: A pilot randomized controlled trial

Phillip Oliver Coffin; Glenn-Milo Santos; Tim Matheson et al.

PLOS ONE, Vol. 12 No. 10 · 2017 · English · PLOS Scopus

Objective: The United States is amidst an opioid epidemic, including synthetic opioids that may result in rapid death, leaving minimal opportunity for bystander rescue. We pilot tested a behavioral intervention to reduce the occurrence of opioid overdose among opioid dependent persons at high-risk…

Can Male Circumcision Have an Impact on the HIV Epidemic in Men Who Have Sex with Men?

Steven M. Goodreau; Nicole B. Carnegie; Eric Vittinghoff et al.

PLoS ONE, Vol. 9 No. 7 · 2014 · English · PLOS Scopus

Background: Three trials have demonstrated the prophylactic effect of male circumcision (MC) for HIV acquisition among heterosexuals, and MC interventions are underway throughout sub-Saharan Africa. Similar efforts for men who have sex with men (MSM) are stymied by the potential for circumcised MSM…

Cigarette and e-cigarette dual use and risk of cardiopulmonary symptoms in the Health eHeart Study

Julie B. Wang; Jeffrey E. Olgin; Gregory Nah et al.

PLOS ONE, Vol. 13 No. 7 · 2018 · English · PLOS Scopus

E-cigarettes are promoted as healthier alternatives to conventional cigarettes. Many cigarette smokers use both products. It is unknown whether the additional use of e-cigarettes among cigarette smokers (dual users) is associated with reduced exposure to tobacco-related health risks…

Illicit opioid use following changes in opioids prescribed for chronic non-cancer pain

Phillip O. Coffin; Christopher Rowe; Natalie Oman et al.

PLOS ONE, Vol. 15 No. 5 · 2020 · English · PLOS Scopus

Background: After decades of increased opioid pain reliever prescribing, providers are rapidly reducing prescribing. We hypothesized that reduced access to prescribed opioid pain relievers among patients previously reliant upon opioid pain relievers would result in increased illicit opioid use…

Pilot study of extended-release lorcaserin for cocaine use disorder among men who have sex with men: A double-blind, placebo-controlled randomized trial

Glenn-Milo Santos; Janet Ikeda; Phillip Coffin et al.

PLOS ONE, Vol. 16 No. 7 · 2021 · English · PLOS Scopus

Objective: To determine if men who have sex with men (MSM) with cocaine use disorder (CUD) and actively-using cocaine could be enrolled and retained in a pharmacologic intervention trial of lorcaserin—a novel 5-HT2cR agonist—and determine the degree to which participants would adhere to study…

Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants

Eugenie Poirot; Eric Vittinghoff; Deus Ishengoma et al.

PLOS ONE, Vol. 10 No. 11 · 2015 · English · PLOS Scopus

Background: Chlorproguanil-dapsone (CD) has been linked to hemolysis in symptomatic glucose-6-phosphate dehydrogenase deficient (G6PDd) children. Few studies have explored the effects of G6PD status on hemolysis in children treated with Intermittent Preventive Treatment in infants (IPTi)…

What Drives the US and Peruvian HIV Epidemics in Men Who Have Sex with Men (MSM)?

Steven M. Goodreau; Nicole B. Carnegie; Eric Vittinghoff et al.

PLoS ONE, Vol. 7 No. 11 · 2012 · English · PLOS Scopus

In this work, we estimate the proportions of transmissions occurring in main vs. casual partnerships, and by the sexual role, infection stage, and testing and treatment history of the infected partner, for men who have sex with men (MSM) in the US and Peru. We use dynamic, stochastic models based…

Correction: What Drives the US and Peruvian HIV Epidemics in Men Who Have Sex with Men (MSM)?

Steven M. Goodreau; Nicole B. Carnegie; Eric Vittinghoff et al.

PLoS ONE, Vol. 8 No. 7 · 2013 · English · PLOS Scopus

Theory-Informed Interventions to Improve the Quality of Tuberculosis Evaluation at Ugandan Health Centers: A Quasi-Experimental Study

Lelia H. Chaisson; Achilles Katamba; Priscilla Haguma et al.

PLOS ONE, Vol. 10 No. 7 · 2015 · English · PLOS Scopus

Background: Tuberculosis (TB) remains under-diagnosed in many countries, in part due to poor evaluation practices at health facilities. Theory-informed strategies are needed to improve implementation of TB evaluation guidelines. We aimed to evaluate the impact of performance feedback and same-day…

Randomized feasibility trial of directly observed versus unobserved hepatitis C treatment with ledipasvir-sofosbuvir among people who inject drugs

Phillip O. Coffin; Glenn-Milo Santos; Emily Behar et al.

PLOS ONE, Vol. 14 No. 6 · 2019 · English · PLOS Scopus

Aims: The advent of direct-acting antivirals for hepatitis C virus (HCV) and limited effectiveness of prevention have generated interest in “Treatment as Prevention” (TasP), in which those most likely to transmit HCV (i.e. people who inject drugs [PWID]) are treated to reduced secondary…

Transmitted Drug Resistance in Persons with Acute/Early HIV-1 in San Francisco, 2002-2009

Vivek Jain; Teri Liegler; Eric Vittinghoff et al.

PLoS ONE, Vol. 5 No. 12 · 2010 · English · PLOS Scopus

Background: Transmitted HIV-1 drug resistance (TDR) is an ongoing public health problem, representing 10–20% of new HIV infections in many geographic areas. TDR usually arises from two main sources: individuals on antiretroviral therapy (ART) who are failing to achieve virologic suppression, and…

Comparing pharmacologic measures of tenofovir exposure in a U.S. pre-exposure prophylaxis randomized trial

Sanjiv M. Baxi; Eric Vittinghoff; Peter Bacchetti et al.

PLOS ONE, Vol. 13 No. 1 · 2018 · English · PLOS Scopus

Clinical trial registration: Clinical Trials.gov NCT00131677

Racial Differences in Left Atrial Size: Results from the Coronary Artery Risk Development in Young Adults (CARDIA) Study

Thomas A. Dewland; Kirsten Bibbins-Domingo; Feng Lin et al.

PLOS ONE, Vol. 11 No. 3 · 2016 · English · PLOS Scopus

Whites have an increased risk of atrial fibrillation (AF) compared to Blacks. The mechanism underlying this association is unknown. Left atrial (LA) size is an important AF risk factor, and studies in older adults suggest Whites have larger LA diameters. However, because AF itself causes LA…