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β-Ionone enhances the inhibitory effects of 5-fluorouracil on the proliferation of gastric adenocarcinoma cells by the GSK-3β signaling pathway

Fa-lin Wang; Xiaoxia Chang; Yuanyang Shi dkk.

PLOS ONE, Vol. 19 No. 9 · 2024 · Inggris · PLOS Scopus

5-Fluorouracil (5-FU) is widely used in the treatment of gastric cancer, and the emergence of drug resistance and toxic effects has limited its application. Therefore, there is an urgent need for safe and effective novel drugs or new therapies. β-Ionone (BI) is found in vegetables and fruits and…