12 hasil untuk "Fatma Moawed"
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Tannic acid nanoparticles improve the renal histological structure and kidney function in arsenic trioxide-induced renal damage
There has been a lot of interest in antioxidant chemicals, especially those that come from natural sources like tannins and polyphenols. In this regard, nanomedicine has helped to uncover novel ways to administer and protect antioxidants. This study looked at the potential benefits and processes of…
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Biochemical Effect of Nicotine on Oxidative Stress and Inflammatory Markers in Lung
Studies regarding nicotine related lung toxic effects are contradictory and limited. This study aimed to evaluate nicotine toxic effect on lung tissues in the light of increased lipid peroxidation (MDA), disrupted antioxidants (GPx, GSH), elevated proinflammatory cytokines (TNF-α, NF-κB) and…
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The potential ameliorating effect of 5-FluorouraciL nanoparticles on 1,2-Dimethylhydrazine- induced hepatotoxicity in rats
Dimethylhydrazine (DMH) is very hazardous to the body's organs, especially the liver. 5-fluorouracil (5-FU) is used to treat breast, brain, liver, and colorectal tumours. The effect of 5-fluorouracil nanogel (5-FUNG) in improving the toxicity effect of 1,2-dimethylhydrazine (DMH) on liver was…
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γ- Radiation exposure Aggravated High-Fat Diet-induced hepatic injury in rats
IIonizing radiation exposure, whether accidental, occupational, or therapeutic, induces direct and indirect alterations. So, this study was carried out to investigate the effect of γ-radiation (IR) exposure on hepatic injury induced by high-fat diet (HFD). Three groups of thirty female Wister rats…
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Protective effect of benzethonium chloride on diethylnitrosamine-induced hepatocellular carcinoma
This study aims to evaluate the protective effect of Benzethonium Chloride (BZC) on- diethylnitrosamine (DEN)‑induced hepatocellular carcinoma. Thirty-two male albino rats were used (eight animal per group). The hepatocarcinogenesis was induced in male Wistar albino rats by DEN (20 mg/kg b.w…
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Ameliorative effect of Cinnamic acid against L-arginine- induced pancreatitis
Acute pancreatitis (AP) is a localized inflammation of the pancreatic gland that often leads to local and systemic complications. Cinnamic acids have been identified as interesting compounds with antioxidant, anti-inflammatory and cytotoxic properties. A pre-clinical study using L-arginine induced…
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Modulatory effect of naringin on L-arginine-induced acute pancreatitis
Among gastrointestinal disorders, acute pancreatitis (AP) is the most frequent reason for hospital admission. It is a terrible, potentially fatal inflammatory disease of the pancreas. The discharge of pancreatic broth into the circulation via AP can cause pancreatic toxemia, which impairs the…
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The potential hepatoprotective and anti-inflammatory role of Quercetin via mitigation of VCAM-1 and Nlrc4 and regulation of SCD1 and G-6-PASE in type 2 diabetic rats.
Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It may be due to impaired insulin secretion, resistance to peripheral actions of insulin, or both. Inflammation and deregulation of glucose metabolism are closely linked to obesity. Lipid buildup makes…
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The potential anti-inflammatory and anti-apoptotic influence of hydrogen sulfide on xenoestrogen induced-toxicity in rats
Hydrogen sulphide (H2S) is a gas transmitter that plays a vital role in a variety of physiological and pathological processes. Xenoestrogen (XE) a regularly used manufacturing chemical, has been related to endocrine disruptor. The purpose of this study was to investigate the effects of H2S donor…
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Calories restriction modulates the enzymatic antioxidant status in D-galactose induced aging in male rats
In postindustrial and modern societies, overeating and high calories consumption has emerged as new challenge in community health. Large effort is now being devoted to detect and evaluate the pathophysiologic consequences of aging and aging accompanying diseases. Several lines of evidence propose…
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Neuromodulatory Influences of vitamin C on D-galactose Induced Neuronal Metabolic Dysfunction Model
Aging is a physiological, non-pathological process that occurs mainly as a slow, gradual, and passive procedure influenced by interplay of numerous genetic and environmental influences. Different ways have been tried to postponement aging and extent life span in animals, dietary anti-oxidants are…
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Ameliorative effect of lemon balm on eltroxin induced-hyperthyroidism in rats
Lemon balm has many therapeutic effects including antimicrobial activity (anti-parasitic, antibacterial, antiviral, antifungal, etc.). Various studies have shown that Lemon balm possesses a high amount of antioxidant activity through its chemical components including highamount of flavonoids…