15 results for "Firman"
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No Evidence of Conpopulation Sperm Precedence between Allopatric Populations of House Mice
Investigations into the evolution of reproductive barriers have traditionally focused on closely related species, and the prevalence of conspecific sperm precedence. The effectiveness of conspecific sperm precedence at limiting gene exchange between species suggests that gametic isolation is an…
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Guidance for good practice in the application of machine learning in development of toxicological quantitative structure-activity relationships (QSARs)
Recent years have seen a substantial growth in the adoption of machine learning approaches for the purposes of quantitative structure-activity relationship (QSAR) development. Such a trend has coincided with desire to see a shifting in the focus of methodology employed within chemical safety…
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Hypothesis generation for rare and undiagnosed diseases through clustering and classifying time-versioned biological ontologies
Rare diseases affect 1-in-10 people in the United States and despite increased genetic testing, up to half never receive a diagnosis. Even when using advanced genome sequencing platforms to discover variants, if there is no connection between the variants found in the patient’s genome and their…
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Similarities and differences in waste composition over time and space determined by multivariate distance analyses
The composition of solid waste affects technology choices and policy decisions regarding its management. Analyses of waste composition studies are almost always made on a parameter by parameter basis. Multivariate distance techniques can create wholisitic determinations of similarities and…
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Incidence and progression of diabetic retinopathy and blindness in Indonesian adults with type 2 diabetes
Objectives: To report the incidence and progression rate of diabetic retinopathy (DR) and blindness in Indonesian adults with type 2 diabetes. Methods: This was a prospective cohort study of 899 adults aged >30 years with confirmed type 2 diabetes. All participants underwent standardized clinical…
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Children and young people’s body mass index measures derived from routine data sources: A national data linkage study in Wales
Background: Routine monitoring of Body Mass Index (BMI) in general practice, and via national surveillance programmes, is essential for the identification, prevention, and management of unhealthy childhood weight. We examined and compared the presence and representativeness of children and young…
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Prevalence of diabetes in pregnancy and microvascular complications in native Indonesian women: The Jogjakarta diabetic retinopathy initiatives in pregnancy (Jog-DRIP)
Objectives: To report the prevalence of total diabetes in pregnancy (TDP) and diabetes-related microvascular complications among Indonesian pregnant women. Methods: We conducted a community-based cross-sectional study with multi-stage, cluster random sampling to select the participating community…
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Protocol for a winter sentinel surveillance program of notifiable respiratory viruses in Queensland
Background: With the reduction in access to polymerase chain reaction (PCR) testing and changes in testing guidelines in Australia, a reduced number of people are seeking testing for coronavirus disease (COVID-19), limiting the opportunity to monitor disease transmission. Knowledge of community…
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Patterns of SARS-CoV-2 seropositivity among essential workers in long term care and retirement homes in Ontario, Canada: A descriptive cross-sectional study
Understanding patterns of SARS-CoV-2 seroprevalence among Long-Term Care Home and Retirement Home (LTCH/RH) staff is critical to designing effective public health interventions. We estimated SARS-CoV-2 seroprevalence among LTCH/RH staff in Ontario, Canada between May 2021-October 2022 using a…
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Loss of the Nuclear Receptor Corepressor SLIRP Compromises Male Fertility
Nuclear receptors (NRs) and their coregulators play fundamental roles in initiating and directing gene expression influencing mammalian reproduction, development and metabolism. SRA stem Loop Interacting RNA-binding Protein (SLIRP) is a Steroid receptor RNA Activator (SRA) RNA-binding protein that…
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Bat detective—Deep learning tools for bat acoustic signal detection
Passive acoustic sensing has emerged as a powerful tool for quantifying anthropogenic impacts on biodiversity, especially for echolocating bat species. To better assess bat population trends there is a critical need for accurate, reliable, and open source tools that allow the detection and…
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AGEMAP: A Gene Expression Database for Aging in Mice
We present the AGEMAP (Atlas of Gene Expression in Mouse Aging Project) gene expression database, which is a resource that catalogs changes in gene expression as a function of age in mice. The AGEMAP database includes expression changes for 8,932 genes in 16 tissues as a function of age. We found…
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Correction: Quantifying Killing of Orangutans and Human-Orangutan Conflict in Kalimantan, Indonesia
Also available at: PLOS
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Quantifying Killing of Orangutans and Human-Orangutan Conflict in Kalimantan, Indonesia
Human-orangutan conflict and hunting are thought to pose a serious threat to orangutan existence in Kalimantan, the Indonesian part of Borneo. No data existed prior to the present study to substantiate these threats. We investigated the rates, spatial distribution and causes of conflict and hunting…