2 hasil untuk "Francesco Musiani"
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Artikel Jurnal Teks lengkap
GOMoDo: A GPCRs Online Modeling and Docking Webserver
G-protein coupled receptors (GPCRs) are a superfamily of cell signaling membrane proteins that include >750 members in the human genome alone. They are the largest family of drug targets. The vast diversity and relevance of GPCRs contrasts with the paucity of structures available: only 21 unique…
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Artikel Jurnal Teks lengkap
Conformational Equilibria in Monomeric α-Synuclein at the Single-Molecule Level
Human α-Synuclein (αSyn) is a natively unfolded protein whose aggregation into amyloid fibrils is involved in the pathology of Parkinson disease. A full comprehension of the structure and dynamics of early intermediates leading to the aggregated states is an unsolved problem of essential importance…