611 hasil untuk "Fu, Yan"
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Artikel Jurnal Teks lengkap
Transferred Subgroup False Discovery Rate for Rare Post-translational Modifications Detected by Mass Spectrometry([Image: see text])
In shotgun proteomics, high-throughput mass spectrometry experiments and the subsequent data analysis produce thousands to millions of hypothetical peptide identifications. The common way to estimate the false discovery rate (FDR) of peptide identifications is the target-decoy database search…
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Class 2 CRISPR/Cas: an expanding biotechnology toolbox for and beyond genome editing
Artificial nuclease-dependent DNA cleavage systems (zinc-finger nuclease, ZFN; transcription activator like effectors, TALENs) and exogenous nucleic acid defense systems (CRISPR/Cas) have been used in the new era for genome modification. The most widely used toolbox for genome editing, modulation…
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Artikel Jurnal Teks lengkap
Effects of Dexmedetomidine on Cognitive Function, Oxidative Stress and Brain Protection in Patients Undergoing Craniocerebral Surgery
BACKGROUND: The protective mechanism of dexmedetomidine on the brains of patients undergoing craniocerebral surgery remains unclear. The aim of this study was to examine the impact of dexmedetomidine on cognitive function, oxidative stress, and brain protection in such patients. METHODS: Fifty-four…
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Artikel Jurnal Teks lengkap
NR1D1 suppressed the growth of ovarian cancer by abrogating the JAK/STAT3 signaling pathway
BACKGROUND: Nuclear receptor subfamily 1 group D member 1 (NR1D1), a nuclear receptor associated with a variety of physiological processes, has a low level in ovarian cancer tissues compared with adjacent normal tissues. However, its role in ovarian cancer remains unclear. METHODS: The level of…
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Artikel Jurnal Teks lengkap
Characterization and stability of approximately dual g-frames in Hilbert spaces
This paper addresses approximately dual g-frames. First, we establish a connection between approximately dual g-frames and dual g-frames and obtain a characterization of approximately dual g-frames. Second, we give results on stability of approximately dual g-frames, which cover the results…
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Artikel Jurnal Teks lengkap
Comparisons of biophysical properties and bioactivities of mono-PEGylated endostatin and an endostatin analog
BACKGROUND: Endostatin (ES) is a well-established potent endogenous antiangiogenic factor. An ES variant, called zinc-binding protein-ES (ZBP-ES), is clinically available; however, its use is limited by rapid renal clearance and short residence time. PEGylation has been exploited to overcome these…
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Artikel Jurnal Teks lengkap
MicroRNA-17-5p induces drug resistance and invasion of ovarian carcinoma cells by targeting PTEN signaling
BACKGROUND: The miR-17-5p was overexpressed in ovarian cancer cells, and those cells were treated with paclitaxel. The proliferation of ovarian cancer cells was assessed by MTT assay. The Caspase-Glo3/7 and TUNEL assay were used to examine the effect of miR-17-5p on paclitaxel-induced apoptosis in…
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Artikel Jurnal Teks lengkap
Transfer posterior error probability estimation for peptide identification
BACKGROUND: In shotgun proteomics, database searching of tandem mass spectra results in a great number of peptide-spectrum matches (PSMs), many of which are false positives. Quality control of PSMs is a multiple hypothesis testing problem, and the false discovery rate (FDR) or the posterior error…
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Endoclip migration after laparoscopic splenectomy combined with pericardial devascularization: Case report and literature review
INTRODUCTION AND IMPORTANCE: Endoclip migration(ECM) after laparoscopic splenectomy combined with pericardial devascularization (LESD) is a rare and dangerous postoperative complication. The emergence of such cases led to our consideration of the timing of use of nonabsorbable endoclips. CASE…
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Downregulated Circulating Long Non-coding RNA GAS6-AS1 Screens and Predicts Acute Myocardial Infarction
BACKGROUND: Acute myocardial infarction seriously threatens human health and life quality, which needs novel biomarkers to improve its early detection and development prediction. This study aimed to assess the potential of long non-coding RNA GAS6-AS1 in discriminating acute myocardial infarction…
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Effects of Autophagy-Related Genes on the Prognosis and Immune Microenvironment of Ovarian Cancer
Ovarian cancer (OC) is among the most malignant tumors of the female reproductive system. The role of autophagy in cancer is complex, and the functional relationship between autophagy-related genes and OC remains unclear. Here, the prognostic value of autophagy-related genes in OC and relationships…
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Approach for determining micro-strength parameters of rock based on particle flow code
Discrete Element Method (DEM) has been successfully utilized to model rock behavior based on particle flow code (PFC), which is extensively employed in solving various problems related to rock engineering and geomechanics. Therefore, a convenient method for selecting appropriate microparameters of…
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Microbial Phagocytic Receptors and Their Potential Involvement in Cytokine Induction in Macrophages
Phagocytosis is an essential process for the uptake of large (>0.5 µm) particulate matter including microbes and dying cells. Specialized cells in the body perform phagocytosis which is enabled by cell surface receptors that recognize and bind target cells. Professional phagocytes play a prominent…
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Artikel Jurnal Teks lengkap
A protocol of using PTMiner for quality control and localization of protein modifications identified by open or closed search of tandem mass spectra
In recent years, an open search of tandem mass spectra has greatly promoted the detection of post-translational modifications (PTMs) in shotgun proteomics. However, post-processing of the results from open searches remains an unsatisfactorily resolved problem, which hinders the open search mode…
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Artikel Jurnal
An underground video image enhancement algorithm
For problems of uneven brightness, blurry detail texture and much noise existed in underground video images, and image distortion, unclear image level and low processing efficiency of common image enhancement algorithm used to process underground video image, an underground video image enhancement…
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Artikel Jurnal
Design of Wireless Strain Sensor with Low Power Consumptio
A design scheme of wireless strain sensor with low power consumption was proposed, which takes MSP430F149 as main controller, nRF24L01 as wireless transmission chip and AD627 as preamplifier. Whole structure of the sensor was given and design methods of software and hardware of data acquisition and…
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Artikel Jurnal
Grey Wolf Optimizer With a Novel Weighted Distance for Global Optimization
In this paper, a new grey wolf optimizer (GWO) variant based on a novel weighted distance (WD) called the GWO-WD algorithm is presented to solve global optimization problems. First, a modified position-updating equation formulated using the proposed strategy is employed to obtain additional…
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Artikel Jurnal
The Research and Improvement of SDT Algorithm for Historical Data in SCADA
With the rapid development of Internet of things and big data technology, the amount of data collected by SCADA(Supervisory Control And Data Acquisition)system is growing exponentially, which the traditional SDT algorithm can not meet the requirements of SCADA system for historical data…
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Artikel Jurnal
Aerobic exercise ameliorates learning and memory deficits of aging rats induced by D-galactose via promoting SYP and BNDF expression in hippocampus
The aim of this study was to explore the effects of aerobic exercise on learning and memory of aging brain and the underlying potential mechanism. We adopted the method of intraperitoneal administration for 6 weeks to induce aging rat model and gave rats swimming exercise intervention in the…
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Artikel Jurnal
Inherent relations between yield stress and stability of bubble petroleum coke water slurry
Abstract The stability of petroleum coke water slurry (PCWS) is currently a hot topic. The inherent relationship between yield stress and stability of bubble-PCWS was studied through orthogonal experiments and range analysis in this work. The results showed that the stability of bubble-PCWS was…