3 hasil untuk "Garba Dauda"
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Artikel Jurnal
In vitro antimalarial activity of phytochemicals from Bombax costatum via inhibition of β-hematin formation
Abstract Malaria continues to pose a major public health challenge, especially in Sub-Saharan Africa, due to increasing resistance to existing therapies such as artemisinin-based treatments. The detoxification of free heme into hemozoin within Plasmodium falciparum is a critical survival mechanism…
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Artikel Jurnal
Inhibition of Phospholipase A2 by Dihydrostilbene Glycoside Isolated from the Ethyl Acetate Fraction of Indigofera capitata: Structural Insights from IR and NMR
Snakebites and subsequent envenomations remain a significant health challenge, especially in rural regions of underdeveloped countries, where they contribute to high mortality rates. In Nigeria, particularly in rural areas, the scarcity of healthcare facilities and antivenoms exacerbates the issue…
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Artikel Jurnal
Molecular docking and dynamics identify novel high-affinity plasmepsin II inhibitors from neem phytochemicals for antimalarial drug development
Abstract Despite advances in ACTs, drug-resistant Plasmodium falciparum strains necessitates new therapeutics. While neem’s broad-spectrum bioactivity is well-known, our recent identification of host-plant synergies prompted this focused investigation into neem’s plasmepsin II inhibitors. This…