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  1. Artikel Jurnal Teks lengkap

    5-Lipoxygenase Inhibitors Attenuate TNF-α-Induced Inflammation in Human Synovial Fibroblasts

    Han-Ching Lin; Tzu-Hung Lin; Ming-Yueh Wu dkk.

    PLoS ONE, Vol. 9 No. 9 · 2014 · Inggris · PLOS Scopus

    The lipoxygenase isoform of 5-lipoxygenase (5-LOX) is reported to be overexpressed in human rheumatoid arthritis synovial tissue and involved in the progress of inflammatory arthritis. However, the detailed mechanism of how 5-lipoxygenase regulates the inflammatory response in arthritis synovial…