4 hasil untuk "Hu, Hui-Rong"
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Artikel Jurnal Teks lengkap
Multi-omics analysis reveals that low cathepsin S expression aggravates sepsis progression and worse prognosis via inducing monocyte polarization
BACKGROUND: Monocytes represent a vital cellular subpopulation in the peripheral blood, crucial in the progression of sepsis. Nonetheless, the prognostic role and precise function of monocytes in sepsis are still inadequately understood. METHODS: Single-cell transcriptomic sequencing and…
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Artikel Jurnal Teks lengkap
Mediation analysis of depressive symptoms in the relationship between pulmonary function (measured by peak expiratory flow) and cognitive function among older adults in Chinese
BACKGROUND: Population aging has led to accelerated decline in pulmonary function, rising prevalence of depressive symptoms, and cognitive impairment, posing significant public health challenges. Although epidemiological evidence links poorer pulmonary function to subsequent cognitive decline, the…
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Artikel Jurnal Teks lengkap
Identification and validation of the important role of tryptophan-related gene CYP1B1 in the development and progression of sepsis
BACKGROUND: Tryptophan metabolism is involved in the progression and immune response of multiple diseases. However, the function of tryptophan metabolism in the immune characteristics of sepsis still needs to be elucidated. METHODS: We collected the datasets from the GEO database to extract data of…
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Artikel Jurnal Teks lengkap
A multi-stage genomic approach to uncover druggable gene targets and neural pathways in postpartum depression
INTRODUCTION: Postpartum depression (PPD) is a severe emotional disorder affecting women worldwide, with significant impacts on maternal and infant health. Its genetic contributors and biological mechanisms are poorly understood. Identifying druggable genes and clarifying their causal roles may…