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3 hasil untuk "Jiann-Ruey Hong"

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  1. Artikel Jurnal Teks lengkap

    Aquatic Birnavirus-Induced ER Stress-Mediated Death Signaling Contribute to Downregulation of Bcl-2 Family Proteins in Salmon Embryo Cells

    Hui Ling Huang; Jen Leih Wu; Mark Hung Chih Chen dkk.

    PLoS ONE, Vol. 6 No. 8 · 2011 · Inggris · PLOS Scopus

    Aquatic birnavirus induces mitochondria-mediated cell death, but whether connects to endoplasmic reticulum (ER) stress is still unknown. In this present, we characterized that IPNV infection triggers ER stress-mediated cell death via PKR/eIF2α phosphorylation signaling for regulating the Bcl-2…

  2. Artikel Jurnal Teks lengkap

    Betanodavirus Induces Oxidative Stress-Mediated Cell Death That Prevented by Anti-Oxidants and Zfcatalase in Fish Cells

    Chih-Wei Chang; Yu-Chin Su; Guor-Mour Her dkk.

    PLoS ONE, Vol. 6 No. 10 · 2011 · Inggris · PLOS Scopus

    The role of oxidative stress in the pathogenesis of RNA nervous necrosis virus infection is still unknown. Red-spotted grouper nervous necrosis virus (RGNNV) induced free radical species (ROS) production at 12–24 h post-infection (pi; early replication stage) in fish GF-1 cells, and then at middle…

  3. Artikel Jurnal Teks lengkap

    Stage-Specific Expression of TNFα Regulates Bad/Bid-Mediated Apoptosis and RIP1/ROS-Mediated Secondary Necrosis in Birnavirus-Infected Fish Cells

    Wei-Lun Wang; Jiann-Ruey Hong; Gen-Hwa Lin dkk.

    PLoS ONE, Vol. 6 No. 2 · 2011 · Inggris · PLOS Scopus

    Infectious pancreatic necrosis virus (IPNV) can induce Bad-mediated apoptosis followed by secondary necrosis in fish cells, but it is not known how these two types of cell death are regulated by IPNV. We found that IPNV infection can regulate Bad/Bid-mediated apoptotic and Rip1/ROS-mediated…