48 hasil untuk "Jing Lin"

Improved FTA Methodology and Application to Subsea Pipeline Reliability Design

Jing Lin; Yongbo Yuan; Mingyuan Zhang

PLoS ONE, Vol. 9 No. 3 · 2014 · Inggris · PLOS Scopus

An innovative logic tree, Failure Expansion Tree (FET), is proposed in this paper, which improves on traditional Fault Tree Analysis (FTA). It describes a different thinking approach for risk factor identification and reliability risk assessment. By providing a more comprehensive and objective…

Methodology to Improve Design of Accelerated Life Tests in Civil Engineering Projects

Jing Lin; Yongbo Yuan; Jilai Zhou dkk.

PLoS ONE, Vol. 9 No. 8 · 2014 · Inggris · PLOS Scopus

For reliability testing an Energy Expansion Tree (EET) and a companion Energy Function Model (EFM) are proposed and described in this paper. Different from conventional approaches, the EET provides a more comprehensive and objective way to systematically identify external energy factors affecting…

Oneself is more important: Exploring the role of narcissism and fear of negative evaluation in the relationship between subjective social class and dishonesty

Song Wu; Jingyuan Liang; Jing Lin dkk.

PLOS ONE, Vol. 14 No. 6 · 2019 · Inggris · PLOS Scopus

Previous studies have found that high social class individuals are more dishonest than low social class ones. However, the underlying mechanism of this phenomenon is still unclear. The “ignoring negative consequences” hypothesis suggests that belonging to a high social class makes individuals…

Knockdown of miR-21-5P targets and regulates PDCD4-induced apoptosis in ovarian granulosa cells and ameliorates in sulin resistance in polycystic ovary syndrom

Hengzhen He; Peng Ning; Xiaohong Chen dkk.

PLOS One, Vol. 21 No. 3 · 2026 · Inggris · PLOS Scopus

This study examined the role of miRNA-21-5p in a rat model of polycystic ovary syndrome with insulin resistance (PCOS-IR) and its potential involvement in ovarian granulosa cell apoptosis. Female Sprague-Dawley rats were divided into four groups, with the PCOS-IR model established using…

Genetic variants of PTGS2, TXA2R and TXAS1 are associated with carotid plaque vulnerability, platelet activation and TXA2 levels in ischemic stroke patients

Xingyang Yi; Jing Lin; Hua Luo dkk.

PLOS ONE, Vol. 12 No. 7 · 2017 · Inggris · PLOS Scopus

Eicosanoids may play a role in ischemic stroke. However, the associations of variants in cyclooxygenase (COX) pathway genes and interaction among these variants with carotid plaque vulnerability are not fully understood. In present study, twelve variants in COX pathway genes were examined using…

Ultrasound-guided stellate ganglion block attenuates early postoperative visceral pain after laparoscopic hysterectomy: A prospective randomized controlled trial

Jing Lin; Yue Huang; Yaling Wen dkk.

PLOS One, Vol. 20 No. 12 · 2025 · Inggris · PLOS Scopus

Background: Postoperative visceral pain remains a major challenge following laparoscopic hysterectomy. While stellate ganglion block (SGB) is increasingly utilized for acute and chronic pain management, limited evidence exists regarding its efficacy in modulating visceral pain after gynecologic…

Aberrant mRNA 5-methylcytosine modification contributes to ovarian dysfunction in a rat model of polycystic ovary syndrome

Xiaohong Chen; Jing Lin; Zhoulin Chi dkk.

PLOS One, Vol. 21 No. 10 · 2026 · Inggris · PLOS Scopus

Objective: This study investigated the altered landscape of messenger RNA 5-methylcytosine (m5C) methylation and the functional involvement of m5C-related regulators in a rat model of polycystic ovary syndrome (PCOS). Methods: A PCOS rat model was established by dehydroepiandrosterone (DHEA)…

Development and validation of a HPLC/FLD method combined with online derivatization for the simple and simultaneous determination of trace amino acids and alkyl amines in continental and marine aerosols

Xiongfeng Huang; Shuh-Ji Kao; Jing Lin dkk.

PLOS ONE, Vol. 13 No. 11 · 2018 · Inggris · PLOS Scopus

A method was developed for simultaneous determination of 15 amino acids and 7 alkyl amines. The method was based on the employment of high performance liquid chromatography/fluorescence detection and online derivatization with o-phthaldiadehyde. The 22 derivatives were separated within 30 min…

A novel catheter with retractable stent that can prevent aortic insufficiency during left ventricular assist

Jing Lin; Zhen Qin; Hong Qian dkk.

PLOS ONE, Vol. 13 No. 4 · 2018 · Inggris · PLOS Scopus

Left ventricle (LV) assist, which refers to the use of a mini-pump or catheter implanted across the aortic valve connected to the pump, can promote myocardial recovery after left ventricle failure. However, conventional LV assist catheters compress the aortic valve, which can induce aortic…

Human Marfan and Marfan-like Syndrome associated mutations lead to altered trafficking of the Type II TGFβ receptor in Caenorhabditis elegans

Jing Lin; Mehul Vora; Nanci S. Kane dkk.

PLOS ONE, Vol. 14 No. 5 · 2019 · Inggris · PLOS Scopus

The transforming growth factor-β (TGFβ) family plays an important role in many developmental processes and when mutated often contributes to various diseases. Marfan syndrome is a genetic disease with an occurrence of approximately 1 in 5,000. The disease is caused by mutations in fibrillin, which…

A miRNA Binding Site Single-Nucleotide Polymorphism in the 3′-UTR Region of the IL23R Gene Is Associated with Breast Cancer

Lihong Wang; Wei Liu; Wei Jiang dkk.

PLoS ONE, Vol. 7 No. 12 · 2012 · Inggris · PLOS Scopus

Background: Research into the etiology of breast cancer has recently focused on the role of the immunity and inflammation. Interleukin-23 and its receptor (IL23R) guide T cells towards the Th17 phenotype. IL23R single nucleotide polymorphisms (SNPs) have been shown to be associated with digestive…

Elevated Klotho Promoter Methylation Is Associated with Severity of Chronic Kidney Disease

Jing Chen; Xiaoyan Zhang; Han Zhang dkk.

PLoS ONE, Vol. 8 No. 11 · 2013 · Inggris · PLOS Scopus

Klotho (KL) expression is down-regulated in the renal tissues of chronic kidney disease (CKD) animal models and patients with end-stage renal disease. The putative role of KL promoter hypermethylation in the progression of CKD remains unclear. The present study aimed to determine renal and…

Identification and characterization of circRNAs in Pyrus betulifolia Bunge under drought stress

Jinxing Wang; Jing Lin; Hong Wang dkk.

PLOS ONE, Vol. 13 No. 7 · 2018 · Inggris · PLOS Scopus

Circular RNAs (circRNAs) play important roles in miRNA function and transcriptional control. However, little is known regarding circRNAs in the pear. In this study, we identified circRNAs using deep sequencing and analyzed their expression under drought stress. We identified 899 circRNAs in total…

Hepatotoxicity of ICI monotherapy or combination therapy in HCC: A systematic review and meta-analysis

Yuping Lu; Jing Lin; Yufeng Lu dkk.

PLOS One, Vol. 20 No. 5 · 2025 · Inggris · PLOS Scopus

Background: The aim of this study was to reveal the hepatotoxicity profile of different immune checkpoint inhibitor (ICI) used strategies in patients with Hepatocellular carcinoma (HCC) by meta-analysis. Methods: Literature was searched through PubMed, Cochrane, Embase, and Web of Science up to…

Physical space interacts with clonal fragmentation and nutrient availability to affect the growth of Salvinia natans

Chao Si; Yu Jin; Jing Lin dkk.

PLOS ONE, Vol. 14 No. 12 · 2019 · Inggris · PLOS Scopus

Physical space, clonal fragmentation and nutrient availability can each affect the growth of clonal plants, but their interactive effect has been little studied. We grew un-fragmented (connected) and fragmented (disconnected) ramet pairs of the floating, clonal plant Salvinia natans in cylindrical…

Correction: Construction and Analysis of High-Complexity Ribosome Display Random Peptide Libraries

Li-Min Yang; Jing-Lin Wang; Lin Kang dkk.

PLoS ONE, Vol. 7 No. 8 · 2012 · Inggris · PLOS Scopus

Identification of Human Fibroblast Cell Lines as a Feeder Layer for Human Corneal Epithelial Regeneration

Rong Lu; Fang Bian; Jing Lin dkk.

PLoS ONE, Vol. 7 No. 6 · 2012 · Inggris · PLOS Scopus

There is a great interest in using epithelium generated in vitro for tissue bioengineering. Mouse 3T3 fibroblasts have been used as a feeder layer to cultivate human epithelia including corneal epithelial cells for more than 3 decades. To avoid the use of xeno-components, we evaluated human…

A Novel Interleukin 33/ST2 Signaling Regulates Inflammatory Response in Human Corneal Epithelium

Jing Lin; Lili Zhang; Guiqiu Zhao dkk.

PLoS ONE, Vol. 8 No. 4 · 2013 · Inggris · PLOS Scopus

Interleukin (IL) 33, a member of IL-1 cytokine family, is well known to promote Th2 type immune responses by signaling through its receptor ST2. However, it is not clear whether ST2 is expressed by mucosal epithelium, and how it responds to IL-33 to induce inflammatory mediators. This study was to…

Catheter Ablation of Idiopathic Premature Ventricular Contractions and Ventricular Tachycardias Originating from the Vicinity of Endocardial and Epicardial Mitral Annulus

Li Yue-Chun; Zheng Cheng; Hong Jun dkk.

PLoS ONE, Vol. 8 No. 11 · 2013 · Inggris · PLOS Scopus

Background: Several previous reports have revealed that idiopathic ventricular arrhythmias (VAs), including premature ventricular contractions (PVCs) and ventricular tachycardias (IVTs), can originate from endocardial mitral annulus (ENDO MA). However, these data are limited to ENDO MA VAs, and…

Construction and Analysis of High-Complexity Ribosome Display Random Peptide Libraries

Li-Min Yang; Jing-Lin Wang; Lin Kang dkk.

PLoS ONE, Vol. 3 No. 5 · 2008 · Inggris · PLOS Scopus

Random peptide libraries displayed on the ribosome are becoming a new tool for the in vitro selection of biologically relevant macromolecules, including epitopes, antagonists, enzymes, and cell-surface receptors. Ribosome display is a cell-free system of coupling individual nascent proteins…