438 hasil untuk "Kumar, Pawan"
Menampilkan 1–20 · 0,69 detik · RSS
-
Artikel Jurnal Teks lengkap
Nano-TiO(2) Doped Chitosan Scaffold for the Bone Tissue Engineering Applications
The present focus is on the synthesis of highly effective, porous, biocompatible, and inert scaffold by using ceramic nanoparticles and natural polymer for the application in tissue engineering. Freeze-drying method was used to fabricate nano-TiO(2) doped chitosan sample scaffold…
-
Artikel Jurnal Teks lengkap
Adult pulmonary tuberculosis as a pathological manifestation of hyperactive antimycobacterial immune response
The intricate relationship between tuberculosis (TB) and immune system remains poorly understood. It is generally believed that weakening of the immune response against Mycobacterium tuberculosis leads to reactivation of latent infection into the active pulmonary disease. However, heterogeneous…
-
Artikel Jurnal Teks lengkap
IFNγ-producing CD4(+) T lymphocytes: the double-edged swords in tuberculosis
IFNγ-producing CD4(+) T cells (IFNγ(+)CD4(+) T cells) are the key orchestrators of protective immunity against Mycobacterium tuberculosis (Mtb). Primarily, these cells act by enabling Mtb-infected macrophages to enforce phagosome-lysosome fusion, produce reactive nitrogen intermediates (RNIs), and…
-
Artikel Jurnal Teks lengkap
A Perspective on the Success and Failure of BCG
TB continues to be one of the major public health threats. BCG is the only available vaccine against TB and confers significant protection against the childhood disease. However, the protective efficacy of BCG against adult pulmonary TB, which represents a larger burden of disease, is highly…
-
Artikel Jurnal Teks lengkap
Regulatory dendritic cells and their usefulness in mitigating solid organ transplant rejection
Dendritic cells (DCs) are highly efficient antigen-presenting cells located throughout body tissues and surfaces. Initial studies described these cells as potent activators of naïve T lymphocytes; however, subsequent research has demonstrated that DCs can also regulate T cell activation, survival…
-
Preprint Teks lengkap
Gas accretion in a clumpy disk with application to AGNs
We analyze the collective gravitational interaction among gas clouds in the inner regions of galactic disks and find that it leads to accretion at a rate $\sim M_{mc}Ω(M_{mc}/M_t)^2$; where $M_{mc}$ is the molecular mass of the disk, $M_t$ is sum of the central plus any axisymmetrically distributed…
-
Preprint Teks lengkap
Excitation of Solar Acoustic Oscillations
The stochastic excitation of solar oscillations due to turbulent convection is reviewed. A number of different observational results that provide test for solar p-mode excitation theories are described. I discuss how well the stochastic excitation theory does in explaining these observations. The…
-
Artikel Jurnal Teks lengkap
Myeloid differentiation primary response protein 88 (MyD88)-deficient dendritic cells exhibit a skewed cytokine response to BCG
OBJECTIVE: Macrophages and dendritic cells (DCs) play key role in the recognition of mycobacterial infection and mounting of antimycobacterial immunity. In case of macrophages, recognition of BCG and other mycobacteria has been attributed predominantly to MyD88-dependent singling. Interestingly, in…
-
Artikel Jurnal Teks lengkap
Sedative-hypnotic Effect of Ash of Silver in Mice: A Reverse Pharmacological Study
Ash of silver is used in traditional systems of medicine for various neurological conditions like insomnias, neuralgias, anxiety disorders, and convulsions. The present study was conducted to evaluate the sedative-hypnotic activity of ash of silver in comparison to pentobarbitone (standard drug) in…
-
Artikel Jurnal Teks lengkap
The role of chemistry in the success of oligonucleotides as therapeutics
-
Artikel Jurnal Teks lengkap
Development of a Novel Pharmacophore Model Guided by the Ensemble of Waters and Small Molecule Fragments Bound to SARS‐CoV‐2 Main Protease
Recent fragment‐based drug design efforts have generated huge amounts of information on water and small molecule fragment binding sites on SARS‐CoV‐2 M(pro) and preference of the sites for various types of chemical moieties. However, this information has not been effectively utilized to develop…
-
Artikel Jurnal Teks lengkap
Potato Periderm Development and Tuber Skin Quality
The periderm is a corky tissue that replaces the epidermis when the latter is damaged, and is critical for preventing pathogen invasion and water loss. The periderm is formed through the meristematic activity of phellogen cells (cork cambium). The potato skin (phellem cells) composes the outer…
-
Artikel Jurnal Teks lengkap
Information diffusion modeling and analysis for socially interacting networks
Social network analysis provides innovative techniques to analyze interactions among entities by emphasizing social relationships. Diffusion in the social network can be referred to spread of information among interconnected nodes or entities in a network. The rate and intensity of diffusion depend…
-
Artikel Jurnal Teks lengkap
Microstructure and electrical properties of microwave sintered Nb-doped NBT ceramics
Nb5+-doped sodium bismuth titanate (NBT) ceramics ((Na0.5Bi0.5)1-x/2Ti1-xNbxO3 where x = 0, 0.005, 0.01 and 0.015) were obtained by microwave assisted solid state reaction route and microwave sintered at 1000 °C. Microwave processing technique was chosen for the sintering as it is a powerfulmethod…
-
Artikel Jurnal Teks lengkap
Efficient Dual Mode Photovoltaic Power System for Improved Drive Span for Electric Vehicles
The problem of drive span maximization in electric vehicle is well studied. There exist number of approaches around the problem which uses residual energy and sleep mode as key in maximizing the drive span. However, they suffer to achieve higher performance in drive span maximization. This article…
-
Artikel Jurnal Teks lengkap
Assessing environmental impacts of offshore wind farms: Lessons learned and recommendations for the future
The worldwide shift towards sustainable energy resources has spurred a notable uptick in the establishment of deep-sea offshore wind farms. Offshore wind power emerges as a hopeful remedy to combat climate change and decrease the reliance on fossil fuels. Nevertheless, the establishment…
-
Artikel Jurnal Teks lengkap
Aerial pollen diversity in India and their clinical significance in allergic diseases
-
Artikel Jurnal Teks lengkap
Cross-Talk Between Antigen Presenting Cells and T Cells Impacts Intestinal Homeostasis, Bacterial Infections, and Tumorigenesis
Innate immunity is maintained in part by antigen presenting cells (APCs) including dendritic cells, macrophages, and B cells. APCs interact with T cells to link innate and adaptive immune responses. By displaying bacterial and tumorigenic antigens on their surface via major histocompatibility…
-
Artikel Jurnal Teks lengkap
Lymphocyte Isolation, Th17 Cell Differentiation, Activation, and Staining
In vitro Th17 (α, β T helper cell which produce IL-17A, IL-17F and IL-22) differentiation has been routinely used for functional T cells studies. Here we describe a method for Th17 cell differentiation.