69 hasil untuk "Kumar Rupesh"
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Precautionary Measures for Successful Open Heart Surgery in G6PD Deficient Patient- A Case Report
Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is among the most common enzymatic disorders of red blood cells. Cardiac surgeries on this group of individuals are associated with an additional risk in terms of impaired oxygenation, prolonged ventilation and increased risk of haemolysis. These…
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Aneurysmal Bone Cyst In Metacarpal of a Child
INTRODUCTION: Aneurysmal bone cyst is a rare, rapidly growing, and destructive benign bone tumor that rarely involves the bones of the hand. Various treatment options for aneurysmal bone cyst have been reported in the literature, but controversy exists regarding optimal treatment. CASE REPORT: A…
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A Mass Causing Right Ventricular Outflow Obstruction - A Dreadful Complication
The most common cardiac tumour in the pediatric age group is rhabdomyoma. These are usually located in the ventricles, either in the ventricular septum or free wall. Cardiac tumours in early infancy may lead to severely compromised blood flow due to inflow or outflow tract obstruction. The…
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Protein network analysis to prioritize key genes in amyotrophic lateral sclerosis
Amyotrophic Lateral Sclerosis (ALS) is a fatal disease, progressive nature characterizes by loss of both upper and lower motor neuron functions. One of the major challenge is to understand the mechanism of ALS multifactorial nature. We aimed to explore some key genes related to ALS through…
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Retrocalcaneal Bursitis due to Rare Calcaneal Osteochondroma in Adult Male : Excision and Outcome
INTRODUCTION: Osteochondroma is the most common benign tumour of the bone and is considered as developmental lesion of the bone. Common site of osteochondroma presentation is around the knee but calcaneal osteochondroma as such is a rare entity. Osteochondromas grow during childhood through…
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Traumatic Transection of Descending Thoracic Aorta: A Rare Cause of Pulmonary Vein Obstruction
Pulmonary vein obstruction is rare condition characterized by challenging diagnosis and unfavorable prognosis at advanced stage. Computerized tomography, magnetic resonance imaging, and transesophageal echocardiography (TEE) are often essential to reach a final diagnosis. External compression of…
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Hotel building design, occupants’ health and performance in response to COVID 19
In the COVID-19 pandemic, the employee realized the importance of a healthy workplace. A healthy workplace provides natural protection against respiratory disease and reduces exposure to viruses. Therefore, the current COVID-19 pandemic should be a wake-up call to understand the importance of…
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Structural transformation of fuzzy analytical hierarchy process: a relevant case for Covid-19
Covid-19 has posed difficult and challenging situations to the supply chains and companies are in fix how to choose the vendors under the uncertainty and complexity in recent years. Therefore, this research aims to incorporate structural transformation of the fuzzy analytical hierarchy process…
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Effect of organic food production and consumption on the affective and cognitive well-being of farmers: analysis using prism of NVivo, etic and emic approach
Extant research studies support has stressed the significance of nourishment on the physical health of humans. Some of the past academic literature has also hinted at an interconnect between food, thoughts, and action that becomes especially significant in the current era of Anthropocene. Organic…
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Local Properties of Vigilance States: EMD Analysis of EEG Signals during Sleep-Waking States of Freely Moving Rats
Understanding the inherent dynamics of the EEG associated to sleep-waking can provide insights into its basic neural regulation. By characterizing the local properties of the EEG using power spectrum, empirical mode decomposition (EMD) and Hilbert-spectral analysis, we can examine the dynamics over…
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Molecular Basis for the Differential Quinolone Susceptibility of Mycobacterial DNA Gyrase
DNA gyrase is a type II topoisomerase that catalyzes the introduction of negative supercoils in the genomes of eubacteria. Fluoroquinolones (FQs), successful as drugs clinically, target the enzyme to trap the gyrase-DNA complex, leading to the accumulation of double-strand breaks in the genome…
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A Mathematical Model towards Understanding the Mechanism of Neuronal Regulation of Wake-NREMS-REMS States
In this study we have constructed a mathematical model of a recently proposed functional model known to be responsible for inducing waking, NREMS and REMS. Simulation studies using this model reproduced sleep-wake patterns as reported in normal animals. The model helps to explain neural…
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Dissecting DNA Compaction by the Bacterial Condensin MukB
Condensins in bacteria are one of the most important factors involved in the organization of long threads of DNA into compact chromosomes. The organization of DNA by condensins is vital to many DNA transactions including DNA repair and chromosome segregation. Although some of the activities of…
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Kissing Lesion of Mitral Valve - A Case Report
Aortic valve endocarditis can lead to secondary involvement of aorto-mitral curtain and the adjacent anterior mitral leaflet (AML). The secondary damage to AML is often caused by the infected jet of aortic regurgitation hitting the ventricular surface of the mitral leaflet, or by the pronounced…
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Intersubunit and intrasubunit interactions driving the MukBEF ATPase
MukBEF, a structural maintenance of chromosome-like protein complex consisting of an ATPase, MukB, and two interacting subunits, MukE and MukF, functions as the bacterial condensin. It is likely that MukBEF compacts DNA via an ATP hydrolysis–dependent DNA loop–extrusion reaction similar to that…
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The MukB-topoisomerase IV interaction mutually suppresses their catalytic activities
The bacterial condensin MukB and the cellular chromosomal decatenase, topoisomerase IV interact and this interaction is required for proper condensation and topological ordering of the chromosome. Here, we show that Topo IV stimulates MukB DNA condensation by stabilizing loops in DNA: MukB alone…
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Experimental vulnerability analysis of QKD based on attack ratings
Inspired by the methodology used for classical cryptographic hardware, we consider the use of attack ratings in the context of QKD security evaluation. To illustrate the relevance of this approach, we conduct an experimental vulnerability assessment of CV-QKD against saturation attacks, for two…
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Delayed Paraparesis: An Unusual Complication Following Coarctation of Aorta Repair
Paraparesis following cardiac surgery is a manifestation of spinal cord injury (SCI). It can occur in any aortic surgery from the aneurysm to the coarctation of the aorta (CoA) where the cross-clamp of the aorta is applied. Though the incidence of paraplegia is low, its occurrence affects the…
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Interrupted Aortic Arch Complicated with Type A Aortic Dissection in a Young Adult
Interrupted aortic arch (IAA) is a congenital anomaly characterized by a discontinuity between the ascending and descending aorta. We present a 27-year-old male patient who had presented with Stanford Type A aortic dissection and was subsequently found to have IAA on computed tomography aortogram…
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Humeral shaft fracture management, a prospective study; nailing or plating
INTRODUCTION: In this fast moving & advancing era no body want to remain handicapped in immobilization by cast with limited movement. As our knowledge is growing, orthopedic implants and appliances also advancing, and creating a very potential options to manage fracture shaft of humerus by internal…