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6 hasil untuk "LI Fu"

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  1. Artikel Jurnal Teks lengkap

    Neoantigens: promising targets for cancer therapy

    Na Xie; Guobo Shen; Wei Gao dkk.

    Signal Transduction and Targeted Therapy · 2023 · Inggris · OpenAlex Scopus

    Recent advances in neoantigen research have accelerated the development and regulatory approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and antibody-based therapies, especially for solid tumors. Neoantigens are newly formed antigens generated by tumor cells as a…

  2. Artikel Jurnal Teks lengkap

    Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management

    Ping Jin; Jingwen Jiang; Li Zhou dkk.

    Journal of Hematology & Oncology · 2022 · Inggris · OpenAlex Scopus

    Drug resistance represents a major obstacle in cancer management, and the mechanisms underlying stress adaptation of cancer cells in response to therapy-induced hostile environment are largely unknown. As the central organelle for cellular energy supply, mitochondria can rapidly undergo dynamic…

  3. Artikel Jurnal Teks lengkap

    ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties

    Guo‐Li Xiong; Zhenhua Wu; Jiacai Yi dkk.

    Nucleic Acids Research · 2021 · Inggris · OpenAlex Scopus

    Because undesirable pharmacokinetics and toxicity of candidate compounds are the main reasons for the failure of drug development, it has been widely recognized that absorption, distribution, metabolism, excretion and toxicity (ADMET) should be evaluated as early as possible. In silico ADMET…

  4. Artikel Jurnal Teks lengkap

    ADMETlab 3.0: an updated comprehensive online ADMET prediction platform enhanced with broader coverage, improved performance, API functionality and decision support

    Li Fu; Shaohua Shi; Jiacai Yi dkk.

    Nucleic Acids Research · 2024 · Inggris · OpenAlex Scopus

    ADMETlab 3.0 is the second updated version of the web server that provides a comprehensive and efficient platform for evaluating ADMET-related parameters as well as physicochemical properties and medicinal chemistry characteristics involved in the drug discovery process. This new release addresses…