378 hasil untuk "LIN, RUI"
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Artikel Jurnal Teks lengkap
Crosstalk between Vitamin D Metabolism, VDR Signalling, and Innate Immunity
The primary function of vitamin D is to regulate calcium homeostasis, which is essential for bone formation and resorption. Although diet is a source of vitamin D, most foods are naturally lacking vitamin D. Vitamin D is also manufactured in the skin through a photolysis process, leading to a…
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Artikel Jurnal Teks lengkap
Quantitative Evaluation of His-Tag Purification and Immunoprecipitation of Tristetraprolin and Its Mutant Proteins from Transfected Human Cells
Histidine (His)-tag is widely used for affinity purification of recombinant proteins, but the yield and purity of expressed proteins are quite different. Little information is available about quantitative evaluation of this procedure. The objective of current study was to evaluate His-tag procedure…
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Artikel Jurnal Teks lengkap
Phosphorylation of Recombinant Tristetraprolin in Vitro
Tristetraprolin/zinc finger protein 36 (TTP/ZFP36) binds and destabilizes some proinflammatory cytokine mRNAs. TTP-deficient mice develop a profound inflammatory syndrome due to excessive production of proinflammatory cytokines. TTP gene expression is induced by various factors including insulin…
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Artikel Jurnal Teks lengkap
Exploring the causal connection: insights into diabetic nephropathy and gut microbiota from whole-genome sequencing databases
Over recent years, the prevalence of diabetes has been on the rise, paralleling improvements in living standards. Diabetic nephropathy (DN), a prevalent complication of diabetes, has also exhibited a growing incidence. While some clinical studies and reviews have hinted at a link between diabetic…
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Artikel Jurnal Teks lengkap
Collaborative interactions to enhance gas binding energy in porous metal–organic frameworks
Metal–organic frameworks (MOFs) are potentially useful materials for hydrogen and methane storage. However, the weak interactions between the MOF host and gas guest molecules have limited their storage capacities at elevated temperatures. In this issue, Alkordi et al. [IUCrJ (2017), 4, 131–135]…
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Artikel Jurnal Teks lengkap
TAGAP restrains myeloid and T cell activation in inflammatory bowel disease
INTRODUCTION: Inflammatory bowel disease (IBD) is characterized by chronic, relapsing inflammation of the gastrointestinal tract. Genetic factors, including variants in T-cell activation Rho GTPase-activating protein (TAGAP), contribute to disease susceptibility and severity. METHODS: A newly…
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Artikel Jurnal Teks lengkap
Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in Citrobacter rodentium-Infected Mice
Disturbed balance between microbiota, epithelial cells, and resident immune cells within the intestine contributes to inflammatory bowel disease (IBD) pathogenesis. The Citrobacter rodentium-induced colitis mouse model has been well documented. This model allows the analysis of host responses to…
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Artikel Jurnal Teks lengkap
Dual-Ascent-Inspired Transformer for Compressed Sensing
Deep learning has revolutionized image compressed sensing (CS) by enabling lightweight models that achieve high-quality reconstruction with low latency. However, most deep neural network-based CS models are pre-trained for specific compression ratios (CS ratios), limiting their flexibility compared…
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Artikel Jurnal Teks lengkap
Canonical pathways and selective mechanisms of autophagy in inflammatory bowel disease
Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disorder of the gastrointestinal tract. Autophagy, an essential intracellular homeostatic process, plays a pivotal role in the pathogenesis and progression of IBD. This review…
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Research on Design Strategies of Cognitive Training System Based on SCD Elderly Behavioral and Psychological Characteristics
Alzheimer’s disease (hereinafter referred to as AD) has become a major global health problem for the elderly. Combining with the current computer-aided design system design for prevention and training of Alzheimer’s disease is one of the important ways to solve this problem. This study aims at the…
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Old Materials for New Functions: Recent Progress on Metal Cyanide Based Porous Materials
Cyanide is the simplest ligand with strong basicity to construct open frameworks including some of the oldest compounds reported in the history of coordination chemistry. Cyanide can form numerous cyanometallates with different transition metal ions showing diverse geometries. Rational design of…
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Altered function of monocytes/macrophages in patients with autoimmune hepatitis
The pathogenesis of autoimmune hepatitis (AIH) involves the intervention of the innate and adaptive immune responses. In the current study, the alterations in monocytes/Kupffer cells (KCs) were investigated in patients with AIH. A total of 21 patients with AIH at different stages of the disease…
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Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis
Background: Autoimmune hepatitis (AIH) is a chronic, progressive, and immunologically mediated inflammatory liver disorder. The etiology of AIH still remains unknown. The aim of this study was to investigate the changes in intestinal permeability, bacterial translocation, and intestinal microbiome…
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Artikel Jurnal Teks lengkap
Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice
Colorectal cancer (CRC) is the fourth leading cause of tumor-related deaths worldwide. In this study, we explored the in vivo effects of quercetin, a plant flavonol from the flavonoid group of polyphenols with antioxidant effects, on colon carcinogenesis induced by azoxymethane/dextran sodium…
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Artikel Jurnal Teks lengkap
Study on the impact of the reserved length of the membranous urethra during laparoscopic radical prostatectomy on the recovery of urinary control function in patients
BACKGROUND: Prostate cancer is a common malignant tumor in the male urogenital system, and laparoscopic radical prostatectomy (LRP) is the standard surgical procedure for early-stage patients. However, postoperative urinary incontinence remains a major complication. The membranous urethra and its…
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Artikel Jurnal
Method of Harmonic Source Identification Based on Harmonic Apparent Power
Based on the harmonic apparent power defined by the IEEE 1459-2010 power standard, the paper proposed a new method of identifying the main harmonic source at the point of common coupling (PCC). Using the reference impedance method, the utility and customer harmonic voltage and current contributions…
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Artikel Jurnal
3D virtual human rapid modeling method based on top-down modeling mechanism
Aiming to satisfy the vast custom-made character demand of 3D virtual human and the rapid modeling in the field of 3D virtual reality, a new virtual human top-down rapid modeling method is put for-ward in this paper based on the systematic analysis of the current situation and shortage of the…
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Artikel Jurnal
Smooth prescribed-time zeroing neural network for solving time-varying nonlinear optimization problems and its applications
In existing prescribed-time zeroing neural networks, the derivative of the computational error with respect to time was found to be discontinuous at the prescribed time when solving time-varying nonlinear optimization problems, which could easily lead to actuator chattering in practical…
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Artikel Jurnal
Smooth prescribed-time zeroing neural network for solving time-varying nonlinear optimization and its applications
In existing prescribed-time zeroing neural networks, the derivative of the computational error with respect to time was found to be discontinuous at the prescribed time when solving time-varying nonlinear optimization problems, which could easily lead to actuator chattering in practical…