13 hasil untuk "LIN Shu-jun"
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Artikel Jurnal
Analysis of Meridians and Acupoints Rules in Acupuncture Treatment of Dysmenorrhea Based on Data Mining
Objective To determine the rules of acupoints and meridians selection for dysmenorrhea based on data mining.Methods The literature on acupuncture treatment of dysmenorrhea was reviewed and a database of dysmenorrhea prescriptions regarding the main points of acupuncture was established with Excel…
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Effect of osmolytes on in-vitro aggregation properties of peptides derived from TGFBIp
Protein aggregation has been one of the leading triggers of various disease conditions, such as Alzheimer’s, Parkinson’s and other amyloidosis. TGFBI-associated corneal dystrophies are protein aggregation disorders in which the mutant TGFBIp aggregates and accumulates in the cornea, leading to a…
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A Split NanoLuc Reporter Quantitatively Measures Circular RNA IRES Translation
Internal ribosomal entry sites (IRESs) are RNA secondary structures that mediate translation independent from the m7G RNA cap. The dicistronic luciferase assay is the most frequently used method to measure IRES-mediated translation. While this assay is quantitative, it requires numerous controls…
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In vivo Pharmacokinetic/Pharmacodynamic (PK/PD) Profiles of Tulathromycin in an Experimental Intraperitoneal Haemophilus parasuis Infection Model in Neutropenic Guinea Pigs
Tulathromycin is a semi-synthetic macrolide antimicrobial that has an important role in veterinary medicine for respiratory disease. The objective of the study was to develop a pharmacokinetic/pharmacodynamic (PK/PD) model to examine the efficacy and determine an optimal dosage of tulathromycin…
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Near infra-red labelling and tracking of corneal endothelial cells in-vivo
Following corneal transplantation, there is an initial, rapid decline in corneal endothelial cells (CECs) following surgery. Direct imaging of post-transplantation endothelial cells is only possible weeks after surgery and with a limited field of view. We have developed a labelling approach using…
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Real-time assessment of corneal endothelial cell damage following graft preparation and donor insertion for DMEK
PURPOSE: To establish a method for assessing graft viability, in-vivo, following corneal transplantation. METHODS: Optimization of calcein AM fluorescence and toxicity assessment was performed in cultured human corneal endothelial cells and ex-vivo corneal tissue. Descemet membrane endothelial…
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Functional Evaluation of Two Corneal Endothelial Cell-Based Therapies: Tissue-Engineered Construct and Cell Injection
Restoration of vision due to corneal blindness from corneal endothelial dysfunction can be achieved via a corneal transplantation. However, global shortage of donor tissues has driven the development cell-based therapeutics. With the capacity to propagate regulatory compliant human corneal…
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Effect of acupuncture on the TLR2/4-NF-κB signalling pathway in a rat model of traumatic brain injury
OBJECTIVE: To study the effect of acupuncture on the TLR2/4-NF-κB signalling pathway in the cortex of Sprague-Dawley rats following traumatic brain injury (TBI), and investigate the possible mechanism underlying the effects of acupuncture on scar repair. METHODS: TBI was established using Feeney’s…
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Regulatory Compliant Tissue-Engineered Human Corneal Endothelial Grafts Restore Corneal Function of Rabbits with Bullous Keratopathy
Corneal transplantation is the only treatment available to restore vision for individuals with blindness due to corneal endothelial dysfunction. However, severe shortage of available donor corneas remains a global challenge. Functional regulatory compliant tissue-engineered corneal endothelial…
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Artikel Jurnal
Effect of acupuncture intervention on neurological function,cerebral microglia activation and secondary nerve damage in traumatic brain injury rats
Objective To observe the effect of acupuncture on activities of microglia in traumatic brain injury(TBI)rats.Methods Fifty-four male SD rats were randomly and equally divided into normal control,model and acupuncture groups according to the random number table(n=18 rats in each group).The TBI model…
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ThermomiR-377-3p-induced suppression of Cirbp expression is required for effective elimination of cancer cells and cancer stem-like cells by hyperthermia
BACKGROUND: In recent years, the development of adjunctive therapeutic hyperthermia for cancer therapy has received considerable attention. However, the mechanisms underlying hyperthermia resistance are still poorly understood. In this study, we investigated the roles of cold‑inducible RNA binding…