18 hasil untuk "LU Ping"
Menampilkan 1–18 · 0,73 detik · RSS
-
Artikel Jurnal Teks lengkap
HIF-1α Inhibition Reduces Nasal Inflammation in a Murine Allergic Rhinitis Model
Background: Hypoxia-inducible factor 1α (HIF-1α) is an important regulator of immune and inflammatory responses. We hypothesized that nasal allergic inflammation is attenuated by HIF-1α inhibition and strengthened by HIF-1α stabilization. Objective: To elucidate the role of HIF-1α in a murine model…
-
Artikel Jurnal Teks lengkap
Borneol Is a TRPM8 Agonist that Increases Ocular Surface Wetness
Borneol is a compound widely used in ophthalmic preparations in China. Little is known about its exact role in treating eye diseases. Here we report that transient receptor potential melastatin 8 (TRPM8) channel is a pharmacological target of borneol and mediates its therapeutic effect in the eyes…
-
Artikel Jurnal Teks lengkap
Dynamic mechanical characteristics and failure mode of serpentine under a three-dimensional high static load and frequent dynamic disturbance
The improved split Hopkinson pressure bar (SHPB) was used to study the dynamic mechanical properties and failure characteristics of surrounding rock in deep rock mass engineering that is under high stress and affected by blasting excavation and other dynamic disturbances. In a three-dimensional…
-
Artikel Jurnal Teks lengkap
Therapeutic Effects of Liposome-Enveloped Ligusticum chuanxiong Essential Oil on Hypertrophic Scars in the Rabbit Ear Model
Hypertrophic scarring, a common proliferative disorder of dermal fibroblasts, results from an overproduction of fibroblasts and excessive deposition of collagen. Although treatment with surgical excision or steroid hormones can modify the symptoms, numerous treatment-related complications have been…
-
Artikel Jurnal Teks lengkap
Study on the proportion of paste filling materials based on fluorogypsum
A new type of paste filling material was created using fluorogypsum, a byproduct of hydrofluoric acid, as the raw material to address the issue of the filling material’s high cost. The effects of five factors, including gangue, fly ash, fluorogypsum, lime content, and mass concentration on the…
-
Artikel Jurnal Teks lengkap
Multi-Parametric Evaluation of Chronic Kidney Disease by MRI: A Preliminary Cross-Sectional Study
Background: The current clinical classification of chronic kidney disease (CKD) is not perfect and may be overestimating both the prevalence and the risk for progressive disease. Novel markers are being sought to identify those at risk of progression. This preliminary study evaluates the…
-
Artikel Jurnal Teks lengkap
Study on the dynamic characteristics of rock surrounding a wellbore in energy storage areas during deep geothermal energy mining
Based on the engineering background in which the rock surrounding a wellbore is affected by a thermal shock, impact disturbances from drilling vibration, cyclic heat extraction and high temperature during hydrothermal geothermal energy mining, the environmental conditions in the shaft wall rock are…
-
Artikel Jurnal Teks lengkap
Identification of Critical Amino Acids in an Immunodominant IgE Epitope of Pen c 13, a Major Allergen from Penicillium citrinum
Background: Pen c 13, identified as a 33-kDa alkaline serine protease, is a major allergen secreted by Penicillium citrinum. Detailed knowledge about the epitopes responsible for IgE binding would help inform the diagnosis/prognosis of fungal allergy and facilitate the rational design of…
-
Artikel Jurnal Teks lengkap
VCP Phosphorylation-Dependent Interaction Partners Prevent Apoptosis in Helicobacter pylori -Infected Gastric Epithelial Cells
Previous studies have demonstrated that valosin-containing protein (VCP) is associated with H. pylori-induced gastric carcinogenesis. By identifying the interactome of VCP overexpressed in AGS cells using a subtractive proteomics approach, we aimed to characterize the cellular responses mediated by…
-
Artikel Jurnal Teks lengkap
Mechanisms Controlling the Effects of Bevacizumab (Avastin) on the Inhibition of Early but Not Late Formed Corneal Neovascularization
Purpose: To evaluate the effects and underlying mechanisms of early and late subconjunctival injection of bevacizumab on the inhibition of corneal neovascularization (NV). Methods: Corneal NV was induced by closed eye contact lens wear followed by a silk suture tarsorrhaphy in rabbits. Weekly…
-
Artikel Jurnal Teks lengkap
Association Study on IL4 , IL13 and IL4RA Polymorphisms in Mite-Sensitized Persistent Allergic Rhinitis in a Chinese Population
Background: The IL4, IL13, and IL4 receptor α chain (IL4RA) genes are candidate genes for atopic diseases. We hypothesized that the polymorphisms in these genes are associated with persistent allergic rhinitis (PER). Objective: To investigate the association of the potential functional…
-
Artikel Jurnal Teks lengkap
Differing Endoplasmic Reticulum Stress Response to Excess Lipogenesis versus Lipid Oversupply in Relation to Hepatic Steatosis and Insulin Resistance
Mitochondrial dysfunction and endoplasmic reticulum (ER) stress have been implicated in hepatic steatosis and insulin resistance. The present study investigated their roles in the development of hepatic steatosis and insulin resistance during de novo lipogenesis (DNL) compared to extrahepatic lipid…
-
Artikel Jurnal Teks lengkap
Small Molecule Amiloride Modulates Oncogenic RNA Alternative Splicing to Devitalize Human Cancer Cells
Alternative splicing involves differential exon selection of a gene transcript to generate mRNA and protein isoforms with structural and functional diversity. Abnormal alternative splicing has been shown to be associated with malignant phenotypes of cancer cells, such as chemo-resistance and…
-
Artikel Jurnal Teks lengkap
High Serum Lipopolysaccharide-Binding Protein Level in Chronic Hepatitis C Viral Infection Is Reduced by Anti-Viral Treatments
Background: Lipopolysaccharide-binding protein (LBP) has been reported to associate with metabolic diseases, such as obesity, diabetes, and non-alcoholic fatty liver disease. Since chronic hepatitis C virus (HCV) infection is associated with metabolic derangements, the relationship between LBP and…
-
Artikel Jurnal Teks lengkap
Association Study on ADAM33 Polymorphisms in Mite-Sensitized Persistent Allergic Rhinitis in a Chinese Population
Background: The ADAM33 gene has been identified as a potentially important asthma candidate gene and polymorphisms in this gene have been shown to be associated with asthma and seasonal allergic rhinitis. Objective: To assess whether the ADAM33 polymorphisms are associated with persistent allergic…
-
Artikel Jurnal Teks lengkap
Hospital Stay as a Proxy Indicator for Severe Injury in Earthquakes: A Retrospective Analysis
Introduction: Earthquakes are the most violent type of natural disasters and injuries are the dominant medical problem in the early phases after earthquakes. However, likely because of poor data availability, high-quality research on injuries after earthquakes is lacking. Length of hospital stay…
-
Artikel Jurnal Teks lengkap
Correction: Hospital Stay as a Proxy Indicator for Severe Injury in Earthquakes: A Retrospective Analysis
-
Artikel Jurnal Teks lengkap
Piwi Is Required in Multiple Cell Types to Control Germline Stem Cell Lineage Development in the Drosophila Ovary
The piRNA pathway plays an important role in maintaining genome stability in the germ line by silencing transposable elements (TEs) from fly to mammals. As a highly conserved piRNA pathway component, Piwi is widely expressed in both germ cells and somatic cells in the Drosophila ovary and is…