378 results for "Lin, Rui"

Crosstalk between Vitamin D Metabolism, VDR Signalling, and Innate Immunity

Lin, Rui

Biomed Res Int · 2016 · English · PubMed Central

The primary function of vitamin D is to regulate calcium homeostasis, which is essential for bone formation and resorption. Although diet is a source of vitamin D, most foods are naturally lacking vitamin D. Vitamin D is also manufactured in the skin through a photolysis process, leading to a…

Quantitative Evaluation of His-Tag Purification and Immunoprecipitation of Tristetraprolin and Its Mutant Proteins from Transfected Human Cells

Cao, Heping; Lin, Rui

Biotechnol Prog · 2009 · English · PubMed Central

Histidine (His)-tag is widely used for affinity purification of recombinant proteins, but the yield and purity of expressed proteins are quite different. Little information is available about quantitative evaluation of this procedure. The objective of current study was to evaluate His-tag procedure…

Phosphorylation of Recombinant Tristetraprolin in Vitro

Cao, Heping; Lin, Rui

Protein J · 2008 · English · PubMed Central

Tristetraprolin/zinc finger protein 36 (TTP/ZFP36) binds and destabilizes some proinflammatory cytokine mRNAs. TTP-deficient mice develop a profound inflammatory syndrome due to excessive production of proinflammatory cytokines. TTP gene expression is induced by various factors including insulin…

Exploring the causal connection: insights into diabetic nephropathy and gut microbiota from whole-genome sequencing databases

Lin, Rui; Chen, Rongping

Ren Fail · 2024 · English · PubMed Central

Over recent years, the prevalence of diabetes has been on the rise, paralleling improvements in living standards. Diabetic nephropathy (DN), a prevalent complication of diabetes, has also exhibited a growing incidence. While some clinical studies and reviews have hinted at a link between diabetic…

Collaborative interactions to enhance gas binding energy in porous metal–organic frameworks

Lin, Rui-Biao; Chen, Banglin

IUCrJ · 2017 · English · PubMed Central

Metal–organic frameworks (MOFs) are potentially useful materials for hydrogen and methane storage. However, the weak interactions between the MOF host and gas guest molecules have limited their storage capacities at elevated temperatures. In this issue, Alkordi et al. [IUCrJ (2017), 4, 131–135]…

TAGAP restrains myeloid and T cell activation in inflammatory bowel disease

Lin, Rui-Ci; Shao, Zhifei

Front Immunol · 2025 · English · PubMed Central

INTRODUCTION: Inflammatory bowel disease (IBD) is characterized by chronic, relapsing inflammation of the gastrointestinal tract. Genetic factors, including variants in T-cell activation Rho GTPase-activating protein (TAGAP), contribute to disease susceptibility and severity. METHODS: A newly…

Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in Citrobacter rodentium-Infected Mice

Lin, Rui; Piao, Meiyu; Song, Yan

Front Microbiol · 2019 · English · PubMed Central

Disturbed balance between microbiota, epithelial cells, and resident immune cells within the intestine contributes to inflammatory bowel disease (IBD) pathogenesis. The Citrobacter rodentium-induced colitis mouse model has been well documented. This model allows the analysis of host responses to…

Dual-Ascent-Inspired Transformer for Compressed Sensing

Lin, Rui; Shen, Yue; Chen, Yu

Sensors (Basel) · 2025 · English · PubMed Central

Deep learning has revolutionized image compressed sensing (CS) by enabling lightweight models that achieve high-quality reconstruction with low latency. However, most deep neural network-based CS models are pre-trained for specific compression ratios (CS ratios), limiting their flexibility compared…

Canonical pathways and selective mechanisms of autophagy in inflammatory bowel disease

Lin, Rui; Xu, Zhaoyuan; Zhi, Min

Adv Biotechnol (Singap) · 2026 · English · PubMed Central

Inflammatory bowel disease (IBD), encompassing Crohn’s disease (CD) and ulcerative colitis (UC), is a chronic inflammatory disorder of the gastrointestinal tract. Autophagy, an essential intracellular homeostatic process, plays a pivotal role in the pathogenesis and progression of IBD. This review…

Research on Design Strategies of Cognitive Training System Based on SCD Elderly Behavioral and Psychological Characteristics

XUE Yanmin; LIN Rui; GE Chang

E3S Web of Conferences, Vol. 179 · 2020 · French · DOAJ

Alzheimer’s disease (hereinafter referred to as AD) has become a major global health problem for the elderly. Combining with the current computer-aided design system design for prevention and training of Alzheimer’s disease is one of the important ways to solve this problem. This study aims at the…

Old Materials for New Functions: Recent Progress on Metal Cyanide Based Porous Materials

Xie, Yi; Lin, Rui‐Biao; Chen, Banglin

Adv Sci (Weinh) · 2021 · English · PubMed Central

Cyanide is the simplest ligand with strong basicity to construct open frameworks including some of the oldest compounds reported in the history of coordination chemistry. Cyanide can form numerous cyanometallates with different transition metal ions showing diverse geometries. Rational design of…

Emerging 2D functional metal-organic framework materials

Liang, Bin; Lin, Rui-Biao; Chen, Banglin

Natl Sci Rev · 2019 · English · PubMed Central

Altered function of monocytes/macrophages in patients with autoimmune hepatitis

LIN, RUI; ZHANG, JIE; ZHOU, LU et al.

Mol Med Rep · 2016 · English · PubMed Central

The pathogenesis of autoimmune hepatitis (AIH) involves the intervention of the innate and adaptive immune responses. In the current study, the alterations in monocytes/Kupffer cells (KCs) were investigated in patients with AIH. A total of 21 patients with AIH at different stages of the disease…

Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis

Lin, Rui; Zhou, Lu; Zhang, Jie et al.

Int J Clin Exp Pathol · 2015 · English · PubMed Central

Background: Autoimmune hepatitis (AIH) is a chronic, progressive, and immunologically mediated inflammatory liver disorder. The etiology of AIH still remains unknown. The aim of this study was to investigate the changes in intestinal permeability, bacterial translocation, and intestinal microbiome…

Quercetin Suppresses AOM/DSS-Induced Colon Carcinogenesis through Its Anti-Inflammation Effects in Mice

Lin, Rui; Piao, Meiyu; Song, Yan et al.

J Immunol Res · 2020 · English · PubMed Central

Colorectal cancer (CRC) is the fourth leading cause of tumor-related deaths worldwide. In this study, we explored the in vivo effects of quercetin, a plant flavonol from the flavonoid group of polyphenols with antioxidant effects, on colon carcinogenesis induced by azoxymethane/dextran sodium…

Study on the impact of the reserved length of the membranous urethra during laparoscopic radical prostatectomy on the recovery of urinary control function in patients

Li, Chuanbo; Lin, Rui; Bai, Qiulei et al.

Front Surg · 2025 · English · PubMed Central

BACKGROUND: Prostate cancer is a common malignant tumor in the male urogenital system, and laparoscopic radical prostatectomy (LRP) is the standard surgical procedure for early-stage patients. However, postoperative urinary incontinence remains a major complication. The membranous urethra and its…

Method of Harmonic Source Identification Based on Harmonic Apparent Power

Xu Lin; Lin Rui Xing; Xu Shuang Ting

E3S Web of Conferences, Vol. 38 · 2018 · French · DOAJ

Based on the harmonic apparent power defined by the IEEE 1459-2010 power standard, the paper proposed a new method of identifying the main harmonic source at the point of common coupling (PCC). Using the reference impedance method, the utility and customer harmonic voltage and current contributions…

3D virtual human rapid modeling method based on top-down modeling mechanism

LI Taotao; FANG Xiongbing; LIN Rui et al.

Zhongguo Jianchuan Yanjiu, Vol. 12 No. 1 · 2017 · Chinese · DOAJ Scopus

Aiming to satisfy the vast custom-made character demand of 3D virtual human and the rapid modeling in the field of 3D virtual reality, a new virtual human top-down rapid modeling method is put for-ward in this paper based on the systematic analysis of the current situation and shortage of the…

Smooth prescribed-time zeroing neural network for solving time-varying nonlinear optimization problems and its applications

Zhong Guomin; Lin Rui; Xiao Likun et al.

Tongxin xuebao (2026) · 2026 · Chinese · DOAJ Scopus

In existing prescribed-time zeroing neural networks, the derivative of the computational error with respect to time was found to be discontinuous at the prescribed time when solving time-varying nonlinear optimization problems, which could easily lead to actuator chattering in practical…

Smooth prescribed-time zeroing neural network for solving time-varying nonlinear optimization and its applications

Zhong Guomin; Lin Rui; Xiao Likun et al.

Tongxin xuebao, Vol. 47 · 2026 · Chinese · DOAJ Scopus

In existing prescribed-time zeroing neural networks, the derivative of the computational error with respect to time was found to be discontinuous at the prescribed time when solving time-varying nonlinear optimization problems, which could easily lead to actuator chattering in practical…