19 hasil untuk "Lin Hu"

Dynamics and Sources of Soil Organic C Following Afforestation of Croplands with Poplar in a Semi-Arid Region in Northeast China

Ya-Lin Hu; Li-Le Hu; De-Hui Zeng

PLoS ONE, Vol. 9 No. 1 · 2014 · Inggris · PLOS Scopus

Afforestation of former croplands has been proposed as a promising way to mitigate rising atmospheric CO2 concentration in view of the commitment to the Kyoto Protocol. Central to this C sequestration is the dynamics of soil organic C (SOC) storage and stability with the development of afforested…

The different outcomes between breast-conserving surgery plus radiotherapy and mastectomy in metaplastic breast cancer: A population-based study

Lin-Yu Xia; Wei-Yun Xu; Qing-Lin Hu

PLOS ONE, Vol. 16 No. 9 · 2021 · Inggris · PLOS Scopus

Background: Metaplastic breast cancer (MBC) are rare. The survival outcomes of MBC patients after breast conserving surgery plus radiotherapy (BCS+RT) or mastectomy have not been established. The study aimed to compare survival outcomes of MBC patients subjected to BCS+RT or mastectomy therapeutic…

Population pharmacokinetics of voriconazole and the role of CYP2C19 genotype on treatment optimization in pediatric patients

Lin Hu; Shiqiong Huang; Qi Huang dkk.

PLOS ONE, Vol. 18 No. 9 · 2023 · Inggris · PLOS Scopus

The aim of this study was to evaluate factors that impact on voriconazole (VRC) population pharmacokinetic (PPK) parameters and explore the optimal dosing regimen for different CYP2C19 genotypes in Chinese paediatric patients. PPK analysis was used to identify the factors contributing to the…

Effects of Nitrogen Addition on Litter Decomposition and CO 2 Release: Considering Changes in Litter Quantity

Hui-Chao Li; Ya-Lin Hu; Rong Mao dkk.

PLOS ONE, Vol. 10 No. 12 · 2015 · Inggris · PLOS Scopus

This study aims to evaluate the impacts of changes in litter quantity under simulated N deposition on litter decomposition, CO2 release, and soil C loss potential in a larch plantation in Northeast China. We conducted a laboratory incubation experiment using soil and litter collected from control…

Rapid Response of Hydrological Loss of DOC to Water Table Drawdown and Warming in Zoige Peatland: Results from a Mesocosm Experiment

Xue-Dong Lou; Sheng-Qiang Zhai; Bing Kang dkk.

PLoS ONE, Vol. 9 No. 11 · 2014 · Inggris · PLOS Scopus

A large portion of the global carbon pool is stored in peatlands, which are sensitive to a changing environment conditions. The hydrological loss of dissolved organic carbon (DOC) is believed to play a key role in determining the carbon balance in peatlands. Zoige peatland, the largest peat store…

Two Half-Sandwiched Ruthenium (II) Compounds Containing 5-Fluorouracil Derivatives: Synthesis and Study of DNA Intercalation

Zhao-Jun Li; Yong Hou; Da-An Qin dkk.

PLOS ONE, Vol. 10 No. 3 · 2015 · Inggris · PLOS Scopus

Two novel coordination compounds of half-sandwiched ruthenium(II) containing 2-(5-fluorouracil)-yl-N-(pyridyl)-acetamide were synthesized, and their intercalation binding modes with calf thymus DNA were revealed by hyperchromism of ultraviolet-visible spectroscopy; the binding constants were…

A novel analytical method to assess the effect of imipenem/cilastatin on liver function laboratory indexes in Chinese underage inpatients: Probability distribution curve

Le Zou; Fanqi Meng; Weici Wang dkk.

PLOS ONE, Vol. 14 No. 10 · 2019 · Inggris · PLOS Scopus

Objectives: The primary objective of this study was to establish a novel method to assess the effect of imipenem/cilastatin (IMP) on liver function laboratory indexes in Chinese underage inpatients (inpatients aged

Mixing Effects of Understory Plant Litter on Decomposition and Nutrient Release of Tree Litter in Two Plantations in Northeast China

Lei Zhao; Ya-Lin Hu; Gui-Gang Lin dkk.

PLoS ONE, Vol. 8 No. 10 · 2013 · Inggris · PLOS Scopus

Understory vegetation plays a crucial role in carbon and nutrient cycling in forest ecosystems; however, it is not clear how understory species affect tree litter decomposition and nutrient dynamics. In this study, we examined the impacts of understory litter on the decomposition and nutrient…

Effects of Type I Collagen Degradation on the Durability of Three Adhesive Systems in the Early Phase of Dentin Bonding

Lin Hu; Yu-hong Xiao; Ming Fang dkk.

PLOS ONE, Vol. 10 No. 2 · 2015 · Inggris · PLOS Scopus

Objective: This study was designed to evaluate the effects of type I collagen degradation on the durability of three adhesive systems in the early phase of dentin bonding. Methods: Bonded dentin specimens were prepared using three different types of adhesive systems. Micro-tensile bond strength and…

Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis

Xu Chen; Shi-Jun Li; David M. Ojcius dkk.

PLOS ONE, Vol. 12 No. 7 · 2017 · Inggris · PLOS Scopus

Objective: To identify the major infiltrating phagocytes during leptospirosis and examine the killing mechanism used by the host to eliminate Leptospira interrogans. Methods: Major infiltrating phagocytes in Leptospira-infected C3H/HeJ mice were detected by immunohistochemistry. Chemokines and…

Inflammatory Stress Increases Hepatic CD36 Translational Efficiency via Activation of the mTOR Signalling Pathway

Chuan Wang; Lin Hu; Lei Zhao dkk.

PLoS ONE, Vol. 9 No. 7 · 2014 · Inggris · PLOS Scopus

Inflammatory stress is an independent risk factor for the development of non-alcoholic fatty liver disease (NAFLD). Although CD36 is known to facilitate long-chain fatty acid uptake and contributes to NAFLD progression, the mechanisms that link inflammatory stress to hepatic CD36 expression and…

Correction: Mononuclear-macrophages but not neutrophils act as major infiltrating anti-leptospiral phagocytes during leptospirosis

Xu Chen; Shi-Jun Li; David M. Ojcius dkk.

PLOS ONE, Vol. 18 No. 9 · 2023 · Inggris · PLOS Scopus

Comparative Genomic Analysis Shows That Avian Pathogenic Escherichia coli Isolate IMT5155 (O2:K1:H5; ST Complex 95, ST140) Shares Close Relationship with ST95 APEC O1:K1 and Human ExPEC O18:K1 Strains

Xiangkai Zhu Ge; Jingwei Jiang; Zihao Pan dkk.

PLoS ONE, Vol. 9 No. 11 · 2014 · Inggris · PLOS Scopus

Avian pathogenic E. coli and human extraintestinal pathogenic E. coli serotypes O1, O2 and O18 strains isolated from different hosts are generally located in phylogroup B2 and ST complex 95, and they share similar genetic characteristics and pathogenicity, with no or minimal host specificity. They…

Construction of an Interspecific Genetic Map Based on InDel and SSR for Mapping the QTLs Affecting the Initiation of Flower Primordia in Pepper ( Capsicum spp.)

Shu Tan; Jiao-Wen Cheng; Li Zhang dkk.

PLOS ONE, Vol. 10 No. 3 · 2015 · Inggris · PLOS Scopus

Re-sequencing permits the mining of genome-wide variations on a large scale and provides excellent resources for the research community. To accelerate the development and application of molecular markers and identify the QTLs affecting the flowering time-related trait in pepper, a total of 1,038…

HTLV-1 Tax Functions as a Ubiquitin E3 Ligase for Direct IKK Activation via Synthesis of Mixed-Linkage Polyubiquitin Chains

Chong Wang; Wenying Long; Chao Peng dkk.

PLOS Pathogens, Vol. 12 No. 4 · 2016 · Inggris · PLOS Scopus

The HTLV-1 oncoprotein Tax plays a key role in CD4+ T cell transformation by promoting cell proliferation and survival, mainly through permanent activation of the NK-κB pathway and induction of many NF-κB target genes. Elucidating the underlying molecular mechanism is therefore critical in…

Eosinophils from Murine Lamina Propria Induce Differentiation of Naïve T Cells into Regulatory T Cells via TGF-β1 and Retinoic Acid

Hong-Hu Chen; Ai-Hua Sun; David M. Ojcius dkk.

PLOS ONE, Vol. 10 No. 11 · 2015 · Inggris · PLOS Scopus

Treg cells play a crucial role in immune tolerance, but mechanisms that induce Treg cells are poorly understood. We here have described eosinophils in lamina propria (LP) that displayed high aldehyde dehydrogenase (ALDH) activity, a rate-limiting step during all-trans retinoic acid (ATRA)…

Identification of a Functional Nuclear Localization Signal Mediating Nuclear Import of the Zinc Finger Transcription Factor ZNF24

Jian-Zhong Li; Xia Chen; Xue-Lian Gong dkk.

PLoS ONE, Vol. 8 No. 11 · 2013 · Inggris · PLOS Scopus

ZNF24 is a member of the SCAN domain family of Krüppel-like zinc finger (ZF) transcription factors, which plays a critical role in cell proliferation and differentiation. However, how ZNF24 enters the nucleus in order to exert its function remains unclear since its nuclear localization signal(s)…

Global Assessment of Antrodia cinnamomea -Induced MicroRNA Alterations in Hepatocarcinoma Cells

Yen-Ju Chen; Mike W. C. Thang; Yu-Tzu Chan dkk.

PLoS ONE, Vol. 8 No. 12 · 2013 · Inggris · PLOS Scopus

Recent studies have demonstrated a potent anticancer potential of medicinal fungus Antrodia cinnamomea, especially against hepatocarcinoma. These studies, however, were performed with prolonged treatments, and the early anticancer events remain missing. To probe the early anticancer mechanisms of…

Gibberellin Overproduction Promotes Sucrose Synthase Expression and Secondary Cell Wall Deposition in Cotton Fibers

Wen-Qin Bai; Yue-Hua Xiao; Juan Zhao dkk.

PLoS ONE, Vol. 9 No. 5 · 2014 · Inggris · PLOS Scopus

Bioactive gibberellins (GAs) comprise an important class of natural plant growth regulators and play essential roles in cotton fiber development. To date, the molecular base of GAs' functions in fiber development is largely unclear. To address this question, the endogenous bioactive GA levels in…