144 hasil untuk "Lin Liu"
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Impacts of climate variability and adaptation strategies on crop yields and soil organic carbon in the US Midwest
Climate change is likely to increase the frequency of drought and more extreme precipitation events. The objectives of this study were i) to assess the impact of extended drought followed by heavy precipitation events on yield and soil organic carbon (SOC) under historical and future climate, and…
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Hydraulic mechanisms of the uneven enrichment of soil organic carbon in sediments during rain-induced overland flow
Organic carbon (OC) can be unevenly enriched in different-sized sediment particles under low-intensity, rain-induced overland flows, but its hydraulic mechanisms are not completely understood. Hence, in this study, the hydraulic transport mechanisms of unevenly enriched OC between different-sized…
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PID-controller enhanced artificial β -cells
Conventional management of diabetes via injection or external insulin pumps suffers from inconvenience and inability to accurately maintain blood glucose levels. A potential solution to these problems consists of implanting synthetic artificial β-cells that can sense glucose and transcribe insulin…
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Gene Decay in Shigella as an Incipient Stage of Host-Adaptation
Background: Many facultative bacterial pathogens have undergone extensive gene decay processes, possibly due to lack of selection pressure during evolutionary conversion from free-living to intracellular lifestyle. Shigella, the causative agents of human shigellosis, have arisen from different E…
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The methylglyoxal pathway is a sink for glutathione in Salmonella experiencing oxidative stress
Salmonella suffer the cytotoxicity of reactive oxygen species generated by the phagocyte NADPH oxidase in the innate host response. Periplasmic superoxide dismutases, catalases and hydroperoxidases detoxify superoxide and hydrogen peroxide (H2O2) synthesized in the respiratory burst of phagocytic…
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Risk-adjusted monitoring of surgical performance
We propose a nonparametric risk-adjusted cumulative sum chart to monitor surgical outcomes for patients with different risks of post-operative mortality due to risk factors that exist before the surgery. Using varying-coefficient logistic regression models, we accomplish the risk adjustment…
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Decomposition of air conditioning electricity consumption considering the dependence between the temperature and electricity consumption
With the continuous increase in air conditioning installations, the proportion of air conditioning electricity consumption to total electricity consumption is growing. Research on the decomposition of air conditioning electricity consumption is of great significance for assessing electricity usage…
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The Inner Nuclear Membrane Protein Src1 Is Required for Stable Post-Mitotic Progression into G1 in Aspergillus nidulans
How membranes and associated proteins of the nuclear envelope (NE) are assembled specifically and inclusively around segregated genomes during exit from mitosis is incompletely understood. Inner nuclear membrane (INM) proteins play key roles by providing links between DNA and the NE. In this study…
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Effects of cognitive impairment and functional limitation on depressive symptoms among community-dwelling older Korean immigrants in the U.S.
The present study examined the effects of cognitive impairment and functional limitation on depressive symptoms among older Korean American immigrants. The sample was drawn from a cross-sectional survey of 210 older Korean immigrants (aged 65 years or older) in Los Angeles County. Based on robust…
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Ensemble Methods for MiRNA Target Prediction from Expression Data
Background: microRNAs (miRNAs) are short regulatory RNAs that are involved in several diseases, including cancers. Identifying miRNA functions is very important in understanding disease mechanisms and determining the efficacy of drugs. An increasing number of computational methods have been…
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Comparison of Metatranscriptomic Samples Based on k- Tuple Frequencies
Background: The comparison of samples, or beta diversity, is one of the essential problems in ecological studies. Next generation sequencing (NGS) technologies make it possible to obtain large amounts of metagenomic and metatranscriptomic short read sequences across many microbial communities. De…
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A user exposure based approach for non-structural road network vulnerability analysis
Aiming at the dense urban road network vulnerability without structural negative consequences, this paper proposes a novel non-structural road network vulnerability analysis framework. Three aspects of the framework are mainly described: (i) the rationality of non-structural road network…
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Characteristics of Soil and Organic Carbon Loss Induced by Water Erosion on the Loess Plateau in China
Soil erosion has been a common environmental problem in the Loess Plateau in China. This study aims to better understand the losses of soil organic carbon (SOC) induced by water erosion. Laboratory-simulated rainfall experiments were conducted to investigate the characteristics of SOC loss induced…
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Whole Genome Mapping with Feature Sets from High-Throughput Sequencing Data
A good physical map is essential to guide sequence assembly in de novo whole genome sequencing, especially when sequences are produced by high-throughput sequencing such as next-generation-sequencing (NGS) technology. We here present a novel method, Feature sets-based Genome Mapping (FGM). With…
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Defect detection method of printed circuit boards based on EDF-YOLOv10
To address the challenges of inadequate feature representation for small objects and slow model convergence in printed circuit board (PCB) defect detection, this paper proposes an improved YOLOv10 algorithm and develops a real-time detection system with a co-optimized hardware and software…
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Genomic Comparison between Salmonella Gallinarum and Pullorum: Differential Pseudogene Formation under Common Host Restriction
Background: Salmonella serovars Enteritidis and Gallinarum are closely related, but their host ranges are very different: the former is host-promiscuous and the latter can infect poultry only. Comparison of their genomic sequences reveals that Gallinarum has undergone much more extensive…
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Xuezhikang, Extract of Red Yeast Rice, Improved Abnormal Hemorheology, Suppressed Caveolin-1 and Increased eNOS Expression in Atherosclerotic Rats
Background: Xuezhikang is the extract of red yeast rice, which has been widely used for the management of atherosclerotic disease, but the molecular basis of its antiatherosclerotic effects has not yet been fully identified. Here we investigated the changes of eNOS in vascular endothelia and RBCs…
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miRLAB: An R Based Dry Lab for Exploring miRNA-mRNA Regulatory Relationships
microRNAs (miRNAs) are important gene regulators at post-transcriptional level, and inferring miRNA-mRNA regulatory relationships is a crucial problem. Consequently, several computational methods of predicting miRNA targets have been proposed using expression data with or without sequence based…
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Complete chloroplast genomes of three important species, Abelmoschus moschatus , A . manihot and A . sagittifolius : Genome structures, mutational hotspots, comparative and phylogenetic analysis in Malvaceae
Abelmoschus is an economically and phylogenetically valuable genus in the family Malvaceae. Owing to coexistence of wild and cultivated form and interspecific hybridization, this genus is controversial in systematics and taxonomy and requires detailed investigation. Here, we present whole…
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Secuer: Ultrafast, scalable and accurate clustering of single-cell RNA-seq data
Identifying cell clusters is a critical step for single-cell transcriptomics study. Despite the numerous clustering tools developed recently, the rapid growth of scRNA-seq volumes prompts for a more (computationally) efficient clustering method. Here, we introduce Secuer, a Scalable and Efficient…