26 hasil untuk "Lin Tang"

Benefits of Therapeutic Drug Monitoring of Vancomycin: A Systematic Review and Meta-Analysis

Zhi-Kang Ye; Hui-Lin Tang; Suo-Di Zhai

PLoS ONE, Vol. 8 No. 10 · 2013 · Inggris · PLOS Scopus

Background and Objective: The necessity of therapeutic drug monitoring (TDM) for vancomycin is controversial. The objective of the current review was to evaluate the available evidence for the necessity of TDM in patients given vancomycin to treat Gram-positive infections. Methods: Medline, Embase…

Effects of the CYP3A4*1B Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Adult Renal Transplant Recipients: A Meta-Analysis

Wei-Long Shi; Hui-Lin Tang; Suo-Di Zhai

PLOS ONE, Vol. 10 No. 6 · 2015 · Inggris · PLOS Scopus

Background and Objective: The association between the CYP3A4*1B single nucleotide polymorphism (SNP) and tacrolimus pharmacokinetics in different studies is controversial. Therefore, a meta-analysis was employed to evaluate the correlation between the CYP3A4*1B genetic polymorphism and tacrolimus…

Studies in RF Power Communication, SAR, and Temperature Elevation in Wireless Implantable Neural Interfaces

Yujuan Zhao; Lin Tang; Robert Rennaker dkk.

PLoS ONE, Vol. 8 No. 11 · 2013 · Inggris · PLOS Scopus

Implantable neural interfaces are designed to provide a high spatial and temporal precision control signal implementing high degree of freedom real-time prosthetic systems. The development of a Radio Frequency (RF) wireless neural interface has the potential to expand the number of applications as…

Efficacy and safety of saxagliptin in patients with type 2 diabetes: A systematic review and meta-analysis

Peng Men; Xiao-tong Li; Hui-lin Tang dkk.

PLOS ONE, Vol. 13 No. 5 · 2018 · Inggris · PLOS Scopus

Objective: To evaluate the comparative efficacy and safety of saxagliptin for type 2 diabetes (T2D). Methods: A systematic search of PubMed, Embase, the Cochrane Library, Web of Science, ClinicalTrials.gov and two Chinese databases for randomized controlled trials (RCTs) comparing saxagliptin with…

Predicting lncRNA-disease associations based on heterogeneous graph convolutional generative adversarial network

Zhonghao Lu; Hua Zhong; Lin Tang dkk.

PLOS Computational Biology, Vol. 19 No. 11 · 2023 · Inggris · PLOS Scopus

There is a growing body of evidence indicating the crucial roles that long non-coding RNAs (lncRNAs) play in the development and progression of various diseases, including cancers, cardiovascular diseases, and neurological disorders. However, accurately predicting potential lncRNA-disease…

Correction: Identification and validation of superior reference gene for gene expression normalization via RT-qPCR in staminate and pistillate flowers of Jatropha curcas – A biodiesel plant

Palaniyandi Karuppaiya; Xiao-Xue Yan; Wang Liao dkk.

PLOS ONE, Vol. 12 No. 5 · 2017 · Inggris · PLOS Scopus

Identification and validation of superior reference gene for gene expression normalization via RT-qPCR in staminate and pistillate flowers of Jatropha curcas – A biodiesel plant

Palaniyandi Karuppaiya; Xiao-Xue Yan; Wang Liao dkk.

PLOS ONE, Vol. 12 No. 2 · 2017 · Inggris · PLOS Scopus

Physic nut (Jatropha curcas L) seed oil is a natural resource for the alternative production of fossil fuel. Seed oil production is mainly depended on seed yield, which was restricted by the low ratio of staminate flowers to pistillate flowers. Further, the mechanism of physic nut flower sex…

Effects of CYP2C19 Loss-of-Function Variants on the Eradication of H. pylori Infection in Patients Treated with Proton Pump Inhibitor-Based Triple Therapy Regimens: A Meta-Analysis of Randomized Clinical Trials

Hui-Lin Tang; Yan Li; Yong-Fang Hu dkk.

PLoS ONE, Vol. 8 No. 4 · 2013 · Inggris · PLOS Scopus

Background: There are inconsistent conclusions about whether CYP2C19 variants could affect H. pylori eradication rate in patients treated with the proton pump inhibitor (PPI)-based therapy. We therefore performed a meta-analysis of randomized clinical trials (RCTs) to re-evaluate the impact of…

Anti-Inflammatory Effects of Ang-(1-7) in Ameliorating HFD-Induced Renal Injury through LDLr-SREBP2-SCAP Pathway

Yaning Zheng; Lin Tang; Wenhan Huang dkk.

PLOS ONE, Vol. 10 No. 8 · 2015 · Inggris · PLOS Scopus

The angiotensin converting enzyme 2-angiotensin-(1–7)-Mas axis (ACE2-Ang-(1–7)-Mas axis) is reported to participate in lipid metabolism in kidney, but its precise effects and underlying mechanisms remain unknown. We hypothesized that Ang-(1–7) reduces lipid accumulation and improves renal injury…

C-type lectin-mediated microbial homeostasis is critical for Helicoverpa armigera larval growth and development

Wenwen Wang; Guijie Wang; Xiaorong Zhuo dkk.

PLOS Pathogens, Vol. 16 No. 9 · 2020 · Inggris · PLOS Scopus

The immune system of a host functions critically in shaping the composition of the microbiota, and some microbes are involved in regulating host endocrine system and development. However, whether the immune system acts on endocrine and development by shaping the composition of the microbiota…

Bacterial Community Associated with Organs of Shallow Hydrothermal Vent Crab Xenograpsus testudinatus near Kuishan Island, Taiwan

Shan-Hua Yang; Pei-Wen Chiang; Tin-Chang Hsu dkk.

PLOS ONE, Vol. 11 No. 3 · 2016 · Inggris · PLOS Scopus

Shallow-water hydrothermal vents off Kueishan Island (northeastern Taiwan) provide a unique, sulfur-rich, highly acidic (pH 1.75–4.6) and variable-temperature environment. In this species-poor habitat, the crab Xenograpsus testudinatus is dominant, as it mainly feeds on zooplankton killed by…

Structural Insights into the Mechanism for Recognizing Substrate of the Cytochrome P450 Enzyme TxtE

Feng Yu; Minjun Li; Chunyan Xu dkk.

PLoS ONE, Vol. 8 No. 11 · 2013 · Inggris · PLOS Scopus

Thaxtomins, a family of phytotoxins produced by Streptomyces spp., can cause dramatic plant cell hypertrophy and seedling stunting. Thaxtomin A is the dominant form from Streptomyces scabies and has demonstrated herbicidal action. TxtE, a cytochrome P450 enzyme from Streptomyces scabies 87.22…

Coronary Injury Score Correlates with Proliferating Cells and Alpha-Smooth Muscle Actin Expression in Stented Porcine Coronary Arteries

Vicki J. Swier; Lin Tang; Kristopher D. Krueger dkk.

PLOS ONE, Vol. 10 No. 9 · 2015 · Inggris · PLOS Scopus

Neointimal formation and cell proliferation resulting into in-stent restenosis is a major pathophysiological event following the deployment of stents in the coronary arteries. In this study, we assessed the degree of injury, based on damage to internal elastic lamina, media, external elastic…

Impact of childhood wheezing on lung function in adulthood: A meta-analysis

Huan Ma; Yuanyuan Li; Lin Tang dkk.

PLOS ONE, Vol. 13 No. 2 · 2018 · Inggris · PLOS Scopus

Background: A growing body of evidence shows that childhood wheezing may lead to recurrent or persistent symptoms in adulthood, such that persistent wheezing associated with lung function deficits often have their roots in the first few years of life. Objectives: We summarized information from…

Diagnosis of Hepatic Angiomyolipoma by Combination of Baseline and Contrast-Enhanced Ultrasound—A Prospective Study in Non-Cirrhotic Patients

Rui Li; Chun-Lin Tang; Yi Zhang dkk.

PLOS ONE, Vol. 10 No. 7 · 2015 · Inggris · PLOS Scopus

Objectives: Hepatic angiomyolipoma (HAML) is a rare, benign mesenchymal tumor of the liver and its diagnosis has been considered challenging. The aim of this study was to investigate prospectively the diagnostic efficacy of the incorporation of both baseline ultrasound (US) and contrast-enhanced…

Comparison of Internal Ribosome Entry Site (IRES) and Furin-2A (F2A) for Monoclonal Antibody Expression Level and Quality in CHO Cells

Steven C. L. Ho; Muriel Bardor; Bin Li dkk.

PLoS ONE, Vol. 8 No. 5 · 2013 · Inggris · PLOS Scopus

Four versions of tricistronic vectors expressing IgG1 light chain (LC), IgG1 heavy chain (HC), and dihydrofolate reductase (DHFR) in one transcript were designed to compare internal ribosome entry site (IRES) and furin-2A (F2A) for their influence on monoclonal antibody (mAb) expression level and…

Altered brain–behavior coupling during inhibitory control in ankylosing spondylitis: ERP evidence from NoGo-P3 component

Lei Zhang; Fang Lu; Yuxin He dkk.

PLOS One, Vol. 21 No. 6 · 2026 · Inggris · PLOS Scopus

Background: Cognitive dysfunction has increasingly been recognized in Ankylosing Spondylitis (AS), yet the neural mechanisms underlying inhibitory control in this population remain insufficiently characterized. Rather than reflecting a simple global deficit, cognitive alterations in AS may involve…

Evaluation of Physicochemical and Antioxidant Properties of Peanut Protein Hydrolysate

Lin Tang; Jie Sun; Hui Cui Zhang dkk.

PLoS ONE, Vol. 7 No. 5 · 2012 · Inggris · PLOS Scopus

Peanut protein and its hydrolysate were compared with a view to their use as food additives. The effects of pH, temperature and protein concentration on some of their key physicochemical properties were investigated. Compared with peanut protein, peanut peptides exhibited a significantly higher…

Production of Functional Soluble Dectin-1 Glycoprotein Using an IRES-Linked Destabilized-Dihydrofolate Reductase Expression Vector

Say Kong Ng; Tessa Rui Min Tan; Yang Wang dkk.

PLoS ONE, Vol. 7 No. 12 · 2012 · Inggris · PLOS Scopus

Dectin-1 (CLEC7A) is a C-type lectin receptor that binds to β-glucans found in fungal cell walls to act as a major pattern recognition receptor (PRR). Since β-glucans epitope is not present in human cells, we are of the opinion that Dectin-1 can have therapeutic functions against fungal infections…

miR-26a Suppresses Tumor Growth and Metastasis by Targeting FGF9 in Gastric Cancer

Min Deng; Hai-lin Tang; Xi-hong Lu dkk.

PLoS ONE, Vol. 8 No. 8 · 2013 · Inggris · PLOS Scopus

The role of miR-26a in cancer cells seemed controversial in previous studies. Until now, the role of miR-26a in gastric cancer remains undefined. In this study, we found that miR-26a was strongly downregulated in gastric cancer (GC) tissues and cell lines, and its expression levels were associated…