6 results for "Lin Teng"
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From climate hazards to early warning: Salmonella as a sentinel for the Climate–AMR–WASH nexus
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Intrinsic Migratory Properties of Cultured Schwann Cells Based on Single-Cell Migration Assay
The migration of Schwann cells is critical for development of peripheral nervous system and is essential for regeneration and remyelination after nerve injury. Although several factors have been identified to regulate Schwann cell migration, intrinsic migratory properties of Schwann cells remain…
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Exploring the Role of Nesprin1 in isoproterenol-induced heart failure: Insights into pathogenesis and therapeutic implications
Objective: This study aimed to investigate the role of Nesprin-1 in the development and progression of isoproterenol (ISO)-induced heart failure (HF) and to elucidate the underlying molecular mechanisms. Methods: HF was induced in mice via daily intraperitoneal injections of ISO (5 mg/kg/day) for…
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Zinc-finger protein 418 overexpression protects against cardiac hypertrophy and fibrosis
Background: This study aimed to investigated the effect and mechanism of zinc-finger protein 418 (ZNF418) on cardiac hypertrophy caused by aortic banding (AB), phenylephrine (PE) or angiotensin II (Ang II) in vivo and in vitro. Methods: The expression of ZNF418 in hearts of patients with dilated…
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Positively-Charged Semi-Tunnel Is a Structural and Surface Characteristic of Polyphosphate-Binding Proteins: An In-Silico Study
Phosphate is essential for all major life processes, especially energy metabolism and signal transduction. A linear phosphate polymer, polyphosphate (polyP), linked by high-energy phosphoanhydride bonds, can interact with various proteins, playing important roles as an energy source and regulatory…
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Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED
Polycomb repressive complex 2 (PRC2), a histone H3 lysine 27 methyltransferase, plays a key role in gene regulation and is a known epigenetics drug target for cancer therapy. The WD40 domain-containing protein EED is the regulatory subunit of PRC2. It binds to the tri-methylated lysine 27 of the…