17 hasil untuk "Lin Zeng"
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Artikel Jurnal Teks lengkap
Genetic Analysis of the Functions and Interactions of Components of the LevQRST Signal Transduction Complex of Streptococcus mutans
Transcription of the genes for a fructan hydrolase (fruA) and a fructose/mannose sugar:phosphotransferase permease (levDEFG) in Streptococcus mutans is activated by a four-component regulatory system consisting of a histidine kinase (LevS), a response regulator (LevR) and two carbohydrate-binding…
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Protoplasmic Astrocytes Enhance the Ability of Neural Stem Cells to Differentiate into Neurons In Vitro
Protoplasmic astrocytes have been reported to exhibit neuroprotective effects on neurons, but there has been no direct evidence for a functional relationship between protoplasmic astrocytes and neural stem cells (NSCs). In this study, we examined neuronal differentiation of NSCs induced by…
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PAIRNet: Predicting PIWI cleavage specificity via position-aware RNA interaction modeling
PIWI proteins maintain genome integrity by piRNA-guided cleavage of complementary RNA targets. While Cleave-N’-Seq (CNS-seq) has advanced our understanding of PIWI targeting logic through quantitative mapping of cleavage rates and pairing rules, its labor-intensive workflows hinder systematic…
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Artikel Jurnal Teks lengkap
Exploration of the B3 transcription factor superfamily in Aquilaria sinensis reveal their involvement in seed recalcitrance and agarwood formation
The endangered tree species of the Aquilaria genus produce agarwood, a high value material produced only after wounding; however, conservation of Aquilaria seeds is difficult. The B3 transcription factor family has diverse important functions in plant development, especially in seed development…
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The Role of PPARγ in Advanced Glycation End Products-Induced Inflammatory Response in Human Chondrocytes
Objective: Advances made in the past ten years highlight the notion that peroxisome proliferator-activated receptors gamma (PPARγ) has protective properties in the pathophysiology of osteoarthritis (OA). The aim of this study was to define the roles of PPARγ in AGEs-induced inflammatory response in…
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Artikel Jurnal Teks lengkap
Development and optimization of sustained release triptolide microspheres
Rheumatoid arthritis is considered a chronic systemic autoimmune disorder that may cause joint destruction. Triptolide, an active component isolated from Tripterygium wilfordii Hook.f., is considered to have promising potential for clinical use in treating rheumatoid arthritis. However, its…
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Gene Regulation by CcpA and Catabolite Repression Explored by RNA-Seq in Streptococcus mutans
A bacterial transcriptome of the primary etiological agent of human dental caries, Streptococcus mutans, is described here using deep RNA sequencing. Differential expression profiles of the transcriptome in the context of carbohydrate source, and of the presence or absence of the catabolite control…
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Diagnostic Accuracy of NT-ProBNP for Heart Failure with Sepsis in Patients Younger than 18 Years
This clinical study investigated plasma NT-proBNP levels as a potential predictor of heart failure in pediatric patients with sepsis. Plasma NT-ProBNP levels of 211 pediatric patients with sepsis and 126 healthy children were measured. Patients were stratified as with heart failure (HF) or without…
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SRplot: A free online platform for data visualization and graphing
Graphics are widely used to provide summarization of complex data in scientific publications. Although there are many tools available for drawing graphics, their use is limited by programming skills, costs, and platform specificities. Here, we presented a freely accessible easy-to-use web server…
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Artikel Jurnal Teks lengkap
Phenotypic Heterogeneity of Genomically-Diverse Isolates of Streptococcus mutans
High coverage, whole genome shotgun (WGS) sequencing of 57 geographically- and genetically-diverse isolates of Streptococcus mutans from individuals of known dental caries status was recently completed. Of the 57 sequenced strains, fifteen isolates, were selected based primarily on differences in…
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Correction: Phenotypic Heterogeneity of Genomically-Diverse Isolates of Streptococcus mutans
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Artikel Jurnal Teks lengkap
Liver Lobe Based Multi-Echo Gradient Recalled Echo T 2 *-Weighted Imaging in Chronic Hepatitis B-Related Cirrhosis: Association with the Presence and Child-Pugh Class of Cirrhosis
Purpose: To investigate whether liver lobe based T2* values measured on gradient recalled echo T2*-weighted imaging are associated with the presence and Child-Pugh class of hepatitis B-related cirrhosis. Methods: Fifty-six patients with hepatitis B-related cirrhosis and 23 healthy control…
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Modeling habitat distribution and niche overlap of Asian horseshoe crabs: Implications for conservation
Asian horseshoe crabs are ancient organisms essential for the balance of marine ecosystems. However, detailed information on their ecology and the environmental factors influencing their distribution remains limited. In this study, we analyzed habitat characteristics, potential distribution, and…
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Spleen Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Method for Staging Liver Fibrosis in a Piglet Model
Objective: To explore spleen hemodynamic alteration in liver fibrosis with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), and to determine how to stage liver fibrosis with spleen DCE-MRI parameters. Materials and Methods: Sixteen piglets were prospectively used to model liver…
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Long non-coding RNA SNHG17 may function as a competitive endogenous RNA in diffuse large B-cell lymphoma progression by sponging miR-34a-5p
We investigated the functional mechanism of long non-coding small nucleolar host gene 17 (SNHG17) in diffuse large B-cell lymphoma (DLBCL). lncRNAs related to the prognosis of patients with DLBCL were screened to analyze long non-coding small nucleolar host gene 17 (SNHG17) expression in DLBCL and…
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Artikel Jurnal Teks lengkap
Quantitative Assessment of the Presence and Severity of Cirrhosis in Patients with Hepatitis B Using Right Liver Lobe Volume and Spleen Size Measured at Magnetic Resonance Imaging
Objective: To determine whether right liver lobe volume (RV) and spleen size measured utilizing magnetic resonance (MR) imaging could identify the presence and severity of cirrhosis in patients with hepatitis B. Methods: Two hundred and five consecutive patients with clinically confirmed diagnosis…