1 hasil untuk "Linlin He"

Glucocorticoid-Induced Leucine Zipper (GILZ) Antagonizes TNF-α Inhibition of Mesenchymal Stem Cell Osteogenic Differentiation

Linlin He; Nianlan Yang; Carlos M. Isales dkk.

PLoS ONE, Vol. 7 No. 3 · 2012 · Inggris · PLOS Scopus

Tumor necrosis factor-alpha (TNF-α) is a potent proinflammatory cytokine that inhibits osteoblast differentiation while stimulating osteoclast differentiation and bone resorption. TNF-α activates MAP kinase pathway leading to inhibition of osterix (Osx) expression. TNF-α also induces the expression…