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  1. Artikel Jurnal

    Amantadine-based combination therapy of Parkinson’s disease to prevent fluctuation and dyskinesia – experiences from a Parkinson outpatient clinic

    Christian Oehlwein; Lucas Netzel; Katrin Mittmann dkk.

    Frontiers in Aging Neuroscience, Vol. 18 · 2026 · Inggris · DOAJ Scopus

    BackgroundThe standard therapy of Parkinson’s disease consists in supplementing the depleted dopamine with oral levodopa. The disadvantages of the levodopa monotherapy – comparable to other dopaminergic substances – are the dose-dependent development of dyskinesia in ON-phases, and bradykinesia and…