9 results for "M. Sayed"
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Knowledge, perceptions and attitude of Egyptian physicians towards biobanking issues
Objectives: Collection and storage of biospecimens and data for biobanking raise many ethical concerns. Stakeholders’ opinions about these ethical issues are important since they can help in the development of ethical guidelines to govern biobanking activities. Physicians are among the important…
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Evaluation of bisphenylthiazoles as a promising class for combating multidrug-resistant fungal infections
To minimize the intrinsic toxicity of the antibacterial agent hydrazinyloxadiazole 1, the hydrazine moiety was replaced with ethylenediamine (compound 7). This replacement generated a potent antifungal agent with no antibacterial activity. Notably, use of a 1,2-diaminocyclohexane moiety, as a…
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MAFLD in Egyptian non-dialysis CKD Patients: Frequency, fibrosis severity, and risk factors
Introduction: The prevalence of Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) in non-dialysis chronic kidney disease (CKD) patients remains underexplored, particularly in high-risk populations such as Egyptians with high rates of metabolic disorders. Aims: This study aimed to…
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The prognosis of lipid reprogramming with the HMG-CoA reductase inhibitor, rosuvastatin, in castrated Egyptian prostate cancer patients: Randomized trial
Aim: The role of surgical castration and rosuvastatin treatment on lipid profile and lipid metabolism related markers was evaluated for their prognostic significance in metastatic prostate cancer (mPC) patients. Methods: A total of 84 newly diagnosed castrated mPC patients treated with castration…
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Factors affecting the choice of delivery place in a rural area in Laos: A qualitative analysis
Background: Home delivery (HD) without skilled birth attendants (SBAs) are considered crucial risk factors increasing maternal and child mortality rates in Loa PDR. While a few studies in the literature discuss the choice of delivery in remote areas of minority ethnic groups; our work aims to…
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Mobility improvement of patients with peripheral visual field losses using novel see-through digital spectacles
Purpose: To evaluate see-through Augmented Reality Digital spectacles (AR DSpecs) for improving the mobility of patients with peripheral visual field (VF) losses when tested on a walking track. Design: Prospective Case Series. Participants: 21 patients with peripheral VF defects in both eyes, with…
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A DFT investigation on the potential of beryllium oxide (Be 12 O 12 ) as a nanocarrier for nucleobases
The study of the interactions between biomolecules and nanostructures is quite fascinating. Herein, the adsorption propensity of beryllium oxide (Be12O12) nanocarrier toward nucleobases (NBs) was investigated. In terms of DFT calculations, the adsorption tendency of Be12O12 toward NBs, including…
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Network pharmacology reveals Ficus. Carica. L latex as a potential therapeutic agent for gastric ulcers by modulating inflammation and promoting repair
The primary objective of our research is to investigate the gastroprotective impact of Ficus. carica L. latex extract (FCL). Metabolic profiling based on HR- LCMS for the extract led to the annotation of 20 compounds. Additionally, the gastro-protective activity of the latex extract was evaluated…
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SuperNatural inhibitors to reverse multidrug resistance emerged by ABCB1 transporter: Database mining, lipid-mediated molecular dynamics, and pharmacokinetics study
An effective approach to reverse multidrug resistance (MDR) is P-glycoprotein (P-gp, ABCB1) transport inhibition. To identify such molecular regulators, the SuperNatural II database, which comprises > 326,000 compounds, was virtually screened for ABCB1 transporter inhibitors. The Lipinski rule was…