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8 hasil untuk "Makaro, Adam"

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  1. Artikel Jurnal Teks lengkap

    Dietary Carbohydrates and Lipids in the Pathogenesis of Leaky Gut Syndrome: An Overview

    Binienda, Agata; Twardowska, Agata; Makaro, Adam dkk.

    Int J Mol Sci · 2020 · Inggris · PubMed Central

    This review summarizes the recent knowledge on the effects of dietary carbohydrates and lipids on the pathophysiology of leaky gut syndrome (LGS). Alterations in intestinal barrier permeability may lead to serious gastrointestinal (GI) disorders. LGS is caused by intestinal hyperpermeability due to…

  2. Artikel Jurnal Teks lengkap

    Regulators of G-Protein Signaling (RGS) in Sporadic and Colitis-Associated Colorectal Cancer

    Swierczynski, Mikolaj; Kasprzak, Zuzanna; Makaro, Adam dkk.

    Int J Mol Sci · 2024 · Inggris · PubMed Central

    Colorectal cancer (CRC) is one of the most common neoplasms worldwide. Among the risk factors of CRC, inflammatory bowel disease (IBD) is one of the most important ones leading to the development of colitis-associated CRC (CAC). G-protein coupled receptors (GPCR) are transmembrane receptors that…

  3. Artikel Jurnal Teks lengkap

    Preventing Bacterial Translocation in Patients with Leaky Gut Syndrome: Nutrition and Pharmacological Treatment Options

    Twardowska, Agata; Makaro, Adam; Binienda, Agata dkk.

    Int J Mol Sci · 2022 · Inggris · PubMed Central

    Leaky gut syndrome is a medical condition characterized by intestinal hyperpermeability. Since the intestinal barrier is one of the essential components maintaining homeostasis along the gastrointestinal tract, loss of its integrity due to changes in bacterial composition, decreased expression…

  4. Artikel Jurnal Teks lengkap

    Walnut Oil Alleviates Intestinal Inflammation and Restores Intestinal Barrier Function in Mice

    Bartoszek, Adrian; Makaro, Adam; Bartoszek, Agnieszka dkk.

    Nutrients · 2020 · Inggris · PubMed Central

    Ulcerative colitis belongs to inflammatory bowel diseases, which is a group of chronic disorders of the gastrointestinal tract. It is a debilitating condition with a wide range of symptoms including rectal bleeding, diarrhea, and visceral pain. Current dietary habits often lead to imbalance in…

  5. Artikel Jurnal Teks lengkap

    Empagliflozin attenuates intestinal inflammation through suppression of nitric oxide synthesis and myeloperoxidase activity in in vitro and in vivo models of colitis

    Makaro, Adam; Świerczyński, Mikołaj; Pokora, Kacper dkk.

    Inflammopharmacology · 2023 · Inggris · PubMed Central

    Inflammatory bowel diseases (IBD) are characterized by chronic and relapsing inflammation affecting the gastrointestinal (GI) tract. The incidence and prevalence of IBD are relatively high and still increasing. Additionally, current therapeutic strategies for IBD are not optimal. These facts urge…

  6. Artikel Jurnal Teks lengkap

    The Role of Chronic Fatigue in Patients with Crohn’s Disease

    Włodarczyk, Marcin; Makaro, Adam; Prusisz, Mateusz dkk.

    Life (Basel) · 2023 · Inggris · PubMed Central

    Crohn’s disease (CD) is a chronic, relapsing disorder belonging to inflammatory bowel diseases (IBD). It is manifested by relapsing transmural inflammation found in any segment of the gastrointestinal tract. Chronic fatigue is a common and underrecognized symptom of CD for which the prevalence is…

  7. Artikel Jurnal Teks lengkap

    Cholesterol Nanofiber Patches with Sustainable Oil Delivery Eliminate Inflammation in Atopic Skin

    Sroczyk, Ewa A.; Tarasiuk, Aleksandra; Talar, Marcin dkk.

    ACS Appl Mater Interfaces · 2024 · Inggris · PubMed Central

    [Image: see text] Atopic skin is dry and itchy and lacks integrity. Impaired skin barrier results from altered lipid composition of the skin. A crucial skin lipid, cholesterol, provides flexibility and homeostasis of the cell membranes’ lipid bilayer. Cholesterol-based creams and natural oils…

  8. Artikel Jurnal Teks lengkap

    Characterization of the Synergistic Effect between Ligands of Opioid and Free Fatty Acid Receptors in the Mouse Model of Colitis

    Binienda, Agata; Makaro, Adam; Talar, Marcin dkk.

    Molecules · 2021 · Inggris · PubMed Central

    Background: Recent studies suggest that lipids, including free fatty acids (FFAs), are necessary for proper μ opioid receptor (MOR) binding and that activation of opioid receptors (ORs) improves intestinal inflammation. The objective of the study was to investigate a possible interaction between…