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Prognostic Significance of Deregulated Dicer Expression in Breast Cancer

Emer Caffrey; Helen Ingoldsby; Deirdre Wall dkk.

PLoS ONE, Vol. 8 No. 12 · 2013 · Inggris · PLOS Scopus

Background: Dicer, an RNase III-type endonuclease, is the key enzyme involved in RNA interference and microRNA pathways. Aberrant expression of Dicer is reported in several human cancers. Our aim was to assess the prognostic role of Dicer in breast cancer. Methods: The entire series comprised 666…