1 results for "Maxwell A. Ruby"

Acute Overactive Endocannabinoid Signaling Induces Glucose Intolerance, Hepatic Steatosis, and Novel Cannabinoid Receptor 1 Responsive Genes

Maxwell A. Ruby; Daniel K. Nomura; Carolyn S. S. Hudak et al.

PLoS ONE, Vol. 6 No. 11 · 2011 · English · PLOS Scopus

Endocannabinoids regulate energy balance and lipid metabolism by stimulating the cannabinoid receptor type 1 (CB1). Genetic deletion and pharmacological antagonism have shown that CB1 signaling is necessary for the development of obesity and related metabolic disturbances. However, the sufficiency…