30 hasil untuk "Melnik, Roderick"
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Preprint Teks lengkap
From Queues to Crowd Flows: Reflected Diffusion Limits for Controlled Agents
We establish a diffusion approximation for a class of multi-agent controlled queueing systems, demonstrating their convergence to a system of interacting reflected Ornstein--Uhlenbeck (OU) processes. The limiting process captures essential behavioral features of the underlying stochastic dynamics…
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Preprint Teks lengkap
Fundamental interactions in self-organized critical dynamics on higher-order networks
In functionally complex systems, higher-order connectivity is often revealed in the underlying geometry of networked units. Furthermore, such systems often show signatures of self-organized criticality, a specific type of non-equilibrium collective behaviour associated with an attractor of internal…
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Artikel Jurnal Teks lengkap
Wettability alteration of calcite oil wells: Influence of smart water ions
Further enhancement of crude oil recovery in the enhanced recovery stage from calcite oil wells is a major global challenge for oil industry. Experimental results suggest that ions present in sea water, also called smart water, have a significant influence on the wettability alteration (less oil…
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Microscopic dynamics modeling unravels the role of asymptomatic virus carriers in SARS-CoV-2 epidemics at the interplay between biological and social factors
The recent experience of SARS-CoV-2 epidemics spreading revealed the importance of passive forms of infection transmissions. Apart from the virus survival outside the host, the latent infection transmissions caused by asymptomatic and presymptomatic hosts represent major challenges for controlling…
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Domain Heterogeneity in Radiofrequency Therapies for Pain Relief: A Computational Study with Coupled Models †
The objective of the current research work is to study the differences between the predicted ablation volume in homogeneous and heterogeneous models of typical radiofrequency (RF) procedures for pain relief. A three-dimensional computational domain comprising of the realistic anatomy of the target…
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Artikel Jurnal Teks lengkap
Microtubule Biomechanics and the Effect of Degradation of Elastic Moduli
The present study aims at quantifying the effect of mechanical degradation of microtubules on their electro-elastic response. A three-dimensional continuum-based hollow cylindrical domain of a microtubule has been considered in this work. A fully coupled electro-mechanical model has been developed…
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Artikel Jurnal Teks lengkap
Modeling latent infection transmissions through biosocial stochastic dynamics
The events of the recent SARS-CoV-2 epidemics have shown the importance of social factors, especially given the large number of asymptomatic cases that effectively spread the virus, which can cause a medical emergency to very susceptible individuals. Besides, the SARS-CoV-2 virus survives for…
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Artikel Jurnal Teks lengkap
Machine Learning for Shape Memory Graphene Nanoribbons and Applications in Biomedical Engineering
Shape memory materials have been playing an important role in a wide range of bioengineering applications. At the same time, recent developments of graphene-based nanostructures, such as nanoribbons, have demonstrated that, due to the unique properties of graphene, they can manifest superior…
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Artikel Jurnal Teks lengkap
Coupled Multiphysics Modelling of Sensors for Chemical, Biomedical, and Environmental Applications with Focus on Smart Materials and Low-Dimensional Nanostructures
Low-dimensional nanostructures have many advantages when used in sensors compared to the traditional bulk materials, in particular in their sensitivity and specificity. In such nanostructures, the motion of carriers can be confined from one, two, or all three spatial dimensions, leading to their…
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Nonlocal models in the analysis of brain neurodegenerative protein dynamics with application to Alzheimer’s disease
It is well known that today nearly one in six of the world’s population has to deal with neurodegenerative disorders. While a number of medical devices have been developed for the detection, prevention, and treatments of such disorders, some fundamentals of the progression of associated diseases…
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Artikel Jurnal Teks lengkap
Spike Timing-Dependent Plasticity and Random Inputs Shape Interspike Interval Regularity of Model STN Neurons
Background/Objectives: Neuronal oscillations play a key role in the symptoms of Parkinson’s disease (PD). This study investigates the effects of random synaptic inputs, their correlations, and the interaction with synaptic dynamics and spike timing-dependent plasticity (STDP) on the membrane…
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Artikel Jurnal Teks lengkap
Complex non‐Markovian dynamics and the dual role of astrocytes in Alzheimer’s disease development and propagation
Alzheimer’s disease (AD) is a common neurodegenerative disorder nowadays. Amyloid‐beta (Aβ) and tau proteins are among the main contributors to the AD progression. In AD, Aβ proteins clump together to form plaques and disrupt cell functions. On the other hand, the abnormal chemical change in the…
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Artikel Jurnal Teks lengkap
Relative importance of grain boundaries and size effects in thermal conductivity of nanocrystalline materials
A theoretical model for describing effective thermal conductivity (ETC) of nanocrystalline materials has been proposed, so that the ETC can be easily obtained from its grain size, single crystal thermal conductivity, single crystal phonon mean free path (PMFP), and the Kaptiza thermal resistance…
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Artikel Jurnal Teks lengkap
Functional Geometry of Human Connectomes
Mapping the brain imaging data to networks, where nodes represent anatomical brain regions and edges indicate the occurrence of fiber tracts between them, has enabled an objective graph-theoretic analysis of human connectomes. However, the latent structure on higher-order interactions remains…
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Artikel Jurnal Teks lengkap
A Neuron-Glial Model of Exosomal Release in the Onset and Progression of Alzheimer's Disease
Exosomes are nano-sized extracellular vesicles that perform a variety of biological functions linked to the pathogenesis of various neurodegenerative disorders. In Alzheimer's disease (AD), for examples, exosomes are responsible for the release of Aβ oligomers, and their extracellular accumulation…
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Artikel Jurnal Teks lengkap
Coarse-Grained Models of RNA Nanotubes for Large Time Scale Studies in Biomedical Applications
In order to describe the physical properties of large time scale biological systems, coarse-grained models play an increasingly important role. In this paper we develop Coarse-Grained (CG) models for RNA nanotubes and then, by using Molecular Dynamics (MD) simulation, we study their physical…
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Artikel Jurnal Teks lengkap
The topology of higher-order complexes associated with brain hubs in human connectomes
Higher-order connectivity in complex systems described by simplexes of different orders provides a geometry for simplex-based dynamical variables and interactions. Simplicial complexes that constitute a functional geometry of the human connectome can be crucial for the brain complex dynamics. In…
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The role of soil surface in a sustainable semiarid ecosystem
Patterns in a semiarid ecosystem are important because they directly and indirectly affect ecological processes, biodiversity, and ecosystem resilience. Understanding the causes and effects of these patterns is critical for long-term land surface management and conservation efforts in semiarid…
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Data-driven Stochastic Model for Quantifying the Interplay Between Amyloid-beta and Calcium Levels in Alzheimer’s Disease
The abnormal aggregation of extracellular amyloid- [Formula: see text] in senile plaques resulting in calcium [Formula: see text] dyshomeostasis is one of the primary symptoms of Alzheimer’s disease (AD). Significant research efforts have been devoted in the past to better understand the underlying…
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Artikel Jurnal Teks lengkap
Coarse-graining RNA nanostructures for molecular dynamics simulations
A series of coarse-grained models have been developed for study of the molecular dynamics of RNA nanostructures. The models in the series have one to three beads per nucleotide and include different amounts of detailed structural information. Such a treatment allows us to reach, for systems of…