1 hasil untuk "Michael Screen"

Molecular Basis of Differential Sensitivity of Myeloma Cells to Clinically Relevant Bolus Treatment with Bortezomib

Tamer B. Shabaneh; Sondra L. Downey; Ayrton L. Goddard dkk.

PLoS ONE, Vol. 8 No. 2 · 2013 · Inggris · PLOS Scopus

The proteasome inhibitor bortezomib (Velcade) is prescribed for the treatment of multiple myeloma. Clinically achievable concentrations of bortezomib cause less than 85% inhibition of the chymotrypsin-like activity of the proteasome, but little attention has been paid as to whether in vitro studies…