136 results for "Mohamad Adam"
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Book Full text
Patient Registry Data for Research: A Basic Practical Guide
Analysis of patient data can be a complicated and challenging process, especially when the data involve many subjects and many variables. A patient registry is a database that organizes collecting the important set of data on a list of identifiable individuals for a specific disease. This type of…
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Book Full text
RECOMMENDATIONS FOR BIOSTATISTICIANS IN MANAGING AND CONDUCTING MEDICAL RESEARCH CONSULTATIONS
One of the determining factors for a successful research output is the design of the research itself. Thus, a researcher, a methodologist or an epidemiologist and a biostatistician may each have his/her own perspective of how to optimize the design of research, by playing an active role in both…
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Journal Article Full text
A Review of Generic Frameworks and Scales for Measuring Quality of Life and Well-Being: Toward Finding the Right Ruler
Assessing quality of life (QOL) and well-being ideally requires considering a broad range of measurable factors. This article reviews the various frameworks of QOL and well-being published in the literature, with the aim of comparing their domains. Moving forward, this study elaborates on the…
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Journal Article
Guidelines for setting cut-off scores in AUC (AUC-GUIDE): balancing sensitivity, specificity, and purpose
Determining ideal cut-off scores is a critical step in screening and diagnostic test evaluation. While the Area Under the Curve (AUC) with Receiver Operating Characteristic (ROC) curve are frequently reported, these do not directly indicate the best threshold for decision-making. In addition…
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Journal Article
Sample Size Determination for Pilot Studies Based on Event Thresholds: A Framework for Evaluating Feasibility of Research Processes
Background: Pilot studies are essential for assessing feasibility and operational processes before large-scale research. This study presents a Poisson-based framework for determining the minimum pilot sample size based on discrete event thresholds. Methods: The number of events represents…
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Journal Article Full text
An elaboration on sample size determination for correlations based on effect sizes and confidence interval width: a guide for researchers
ObjectivesThis paper aims to serve as a useful guide for sample size determination for various correlation analyses that are based on effect sizes and confidence interval width.Materials and MethodsSample size determinations are calculated for Pearson’s correlation, Spearman’s rank correlation, and…
Also available at: PubMed Central
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Journal Article Full text
Key strategies for addressing the rising global burden and cost of healthcare
The continuous rise in healthcare costs has become a global concern, posing significant challenges to both developed and developing nations. This upward trend is driven by various factors, including an aging population, advancements in drugs and medical technology, the increased prevalence of…
Also available at: PubMed Central
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Journal Article Full text
From Biomarker Discovery to Targeted Clinical Application: Addressing Translational Gaps in Early Cancer Detection
Despite extensive progress in breast cancer biomarker research, only a limited proportion of candidate biomarkers successfully transition from early discovery to clinically validated tools for targeted early detection. This article examines the key translational barriers that impede this…
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Journal Article Full text
An Elaboration on Sample Size Planning for Performing a One-Sample Sensitivity and Specificity Analysis by Basing on Calculations on a Specified 95% Confidence Interval Width
Sample size calculation based on a specified width of 95% confidence interval will offer researchers the freedom to set the level of accuracy of the statistics that they aim to achieve for a particular study. This paper provides a description of the general conceptual context for performing…
Also available at: PubMed Central
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Book Full text
Development of Questionnaires for Quantitative Medical Research
In research, a questionnaire is an important instrument for collecting data. The quality of the questionnaire has an impact on data collecting success and, ultimately, on the study's objectives (s). The overall approach to developing four types of questionnaires for quantitative research is…
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Journal Article Full text
A Step-by-Step Process on Sample Size Determination for Medical Research
Determination of a minimum sample size required for a study is a major consideration which all researchers are confronted with at the early stage of developing a research protocol. This is because the researcher will need to have a sound prerequisite knowledge of inferential statistics in order to…
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Journal Article Full text
The Dilemma and Wisdom in Translating p Values: A Collaborative Approach to Strengthening Scientific Validity
The p value remains a widely used statistical tool for assessing the significance of research findings, yet its interpretation and application often provoke debate. While the p value provides a measure of evidence against the null hypothesis, it does not convey essential information about the…
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Journal Article
Dissecting implementation musharakah in Islamic bank in Indonesia: a case study
This study aims to analyze whether musharakah financing applications implemented by Islamic banks in Indonesia have met the requirements of Sharia standards as stipulated in the National Sharia Council Fatwa (DSN) Number 8, Sharia Accounting Standard Number 106 and Financial Accounting Standards…
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Journal Article
Guidelines of the minimum sample size requirements for Kappa agreement test
Background and aims: To estimate sample size for Cohen’s kappa agreement test can be challenging especially when it is expected that the true marginal rating frequencies are not the same. This study aims to present the tables that display a minimum sample size determination for an agreement test…
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Journal Article Full text
An Application of the Runs Test to Test for Randomness of Observations Obtained from a Clinical Survey in an Ordered Population
Runs test is a statistical procedure which determines whether a sequence of data within a given distribution have been derived with a random process or not. It may be applied to test the randomness of data in a survey that collect data from an ordered population. This article illustrates on method…