3 hasil untuk "Moize, Burhanuddin"
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Artikel Jurnal Teks lengkap
Critical Role of Striatin in Blood Pressure and Vascular Responses to Dietary Sodium Intake
Striatin is a protein regulator of vesicular trafficking in neurons that also binds caveolin-1 and Ca(2+)-calmodulin, and could activate eNOS. We have shown that striatin colocalizes with the mineralocorticoid receptor, and that mineralocorticoid receptor activation increases striatin levels in…
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Artikel Jurnal Teks lengkap
Striatin heterozygous mice are more sensitive to aldosterone-induced injury
Aldosterone modulates the activity of both epithelial (specifically renal) and non-epithelial cells. Binding to the mineralocorticoid receptor (MR), activates two pathways: the classical genomic and the rapidly activated non-genomic that is substantially modulated by the level of striatin. We…
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Artikel Jurnal Teks lengkap
Variants in Striatin Gene are Associated with Salt Sensitive Blood Pressure in Mice and Humans
Striatin is a novel protein that interacts with steroid receptors and modifies rapid, non-genomic activity in vitro. We tested the hypothesis that striatin would in turn affect mineralocorticoid receptor function and consequently sodium, water, and blood pressure homeostasis in an animal model. We…