10 results for "Muhammad, Idrees"
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P2X4 receptors mediate induction of antioxidants, fibrogenic cytokines and ECM transcripts; in presence of replicating HCV in in vitro setting: An insight into role of P2X4 in fibrosis
Background & aims: Major HCV infections lead to chronic hepatitis, which results in progressive liver disease including fibrosis, cirrhosis and eventually hepatocellular carcinoma (HCC). P2X4 and P2X7 are most widely distributed receptors on hepatocytes. Methods: Full length P2X4 (1.7kb) (Rattus…
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Computational Prediction and Analysis of Envelop Glycoprotein Epitopes of DENV-2 and DENV-3 Pakistani Isolates: A First Step towards Dengue Vaccine Development
Dengue fever of tropics is a mosquito transmitted devastating disease caused by dengue virus (DENV). There is no effective vaccine available, so far, against any of its four serotypes (DENV-1, DENV-2, DENV-3, and DENV-4). There is a need for the development of preventive and therapeutic vaccines…
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Forecasting stock prices using long short-term memory involving attention approach: An application of stock exchange industry
The Stability of the economy is always a great challenge across the world, especially in under developed countries. Many researchers have contributed to forecasting the Stock Market and controlling the situation to ensure economic stability over the past several decades. For this purpose, many…
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Design of a novel compact highly selective wideband bandstop RF filter using dual path lossy resonator for next generation applications
This article presents the design of a wideband bandstop RF filter intending to improve selectivity and compactness. Conventional bandstop filter topology with finite unloaded quality factor produces degraded bandstop filter performance due to dissipation loss. In the proposed filter design, a novel…
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Gene expression and anticancer evaluation of Kigelia africana (Lam.) Benth. Extracts using MDA-MB-231 and MCF-7 cell lines
In recent years, a cancer research trend has shifted towards identifying novel therapeutic compounds from natural assets for the management of cancer. In this study, we aimed to assess the cytotoxic activity of Kigelia Africana (KA) extracts on breast cancer (MDA-MB-231 and MCF-7) and noncancerous…
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Effect of exogenous alpha-tocopherol on physio-biochemical attributes and agronomic performance of lentil ( Lens culinaris Medik.) under drought stress
Water being a vital part of cell protoplasm plays a significant role in sustaining life on earth; however, drastic changes in climatic conditions lead to limiting the availability of water and causing other environmental adversities. α-tocopherol being a powerful antioxidant, protects lipid…
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Seroepidemiology and associated risk factors of hepatitis B and C virus infections among pregnant women attending maternity wards at two hospitals in Swabi, Khyber Pakhtunkhwa, Pakistan
Background & aim: Hepatitis B and C infections are global issues that are associated with a massive financial burden in developing countries where vertical transmission is the major mode and remains high. This cross-sectional study was designed to investigate the seroepidemiology and associated…
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Health risk assessment of heavy metals via consumption of dietary vegetables using wastewater for irrigation in Swabi, Khyber Pakhtunkhwa, Pakistan
Health assumptions to the population due to the utilization of contaminated vegetables have been a great concern all over the world. In this study, an investigation has been conducted to ascertain metal concentrations in the wastewater, soil and commonly consumed vegetables from the vicinity of…
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Phylogenetic analysis and antimicrobial susceptibility profile of uropathogens
The uropathogens is the main cause of urinary tract infection (UTI). The aim of the study was to isolate bacteria from urine samples of UTI patients and find out the susceptibility of isolated bacteria. Bacteria were identified using both conventional and molecular methods. Sanger sequence…
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Socio-demographic determinants of Monkeypox virus preventive behavior: A cross-sectional study in Pakistan
Background: Monkeypox (mpox), re-emerging zoonotic infectious disease, is striking the world with serious public health concerns, especially in non-endemic countries. The public’s knowledge and attitude towards the monkeypox virus (MPXV) influence their adherence to preventive strategies…